STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (326 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.998
bioA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Coenzyme metabolism; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 0.986
birA
Biotin-(acetyl-CoA carboxylase) ligase; Coenzyme metabolism.
  
 
 0.940
bioF
8-amino-7-oxononanoate synthase; Coenzyme metabolism.
  
 0.881
dacA
Uncharacterized conserved membrane protein, possible metal dependent phosphoesterase; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
     
 0.813
uppS
Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
       0.812
CAK27697.1
Predicted sulfurtransferase; Belongs to the UPF0176 family.
       0.790
cysD
O-Acetyl homoserine sulfhydrylase; Amino acid transport and metabolism.
       0.786
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
     
 0.782
CAK27700.1
Putative glutathione S-transferase; Fused with a domain of Unknown function.
       0.735
Your Current Organism:
Synechococcus sp. RCC307
NCBI taxonomy Id: 316278
Other names: S. sp. RCC307, Synechococcus sp. MINSyn016-15m-01 substr. AC6A1
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