STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemL,Glutamate-1-semialdehyde 2,1-aminomutase; Coenzyme metabolism; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (434 aa)    
Predicted Functional Partners:
hemB
Delta-aminolevulinic acid dehydratase; Coenzyme metabolism; Belongs to the ALAD family.
 
 
 0.995
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.993
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
 
  
 0.947
fcbT1
TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component; Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
       0.768
fcbT2
TRAP-type mannitol/chloroaromatic compound transport system, small permease component; Secondary metabolites biosynthesis, transport, and catabolism.
       0.768
fcbT3
TRAP-type mannitol/chloroaromatic compound transport system, large permease component; Secondary metabolites biosynthesis, transport, and catabolism.
       0.768
lysC
Aspartokinase; Amino acid transport and metabolism.
   
 
 0.695
hemD
Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
  
 0.659
CAK28356.1
Uncharacterized conserved membrane protein.
 
      0.630
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.623
Your Current Organism:
Synechococcus sp. RCC307
NCBI taxonomy Id: 316278
Other names: S. sp. RCC307, Synechococcus sp. MINSyn016-15m-01 substr. AC6A1
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