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hisH protein (Synechococcus sp. CC9902) - STRING interaction network
"hisH" - Imidazole glycerol phosphate synthase subunit HisH in Synechococcus sp. CC9902
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (213 aa)    
Predicted Functional Partners:
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (258 aa)
  0.999
hisI
annotation not available (222 aa)
   
  0.999
hisA
annotation not available (263 aa)
 
  0.998
hisB
annotation not available (201 aa)
 
 
  0.997
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (446 aa)
   
  0.989
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity; Belongs to the ATP phosphoribosyltransferase family. Short subfamily (216 aa)
 
   
  0.933
ABB25686.1
annotation not available (222 aa)
   
        0.885
purH
annotation not available (520 aa)
       
    0.834
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (175 aa)
       
  0.822
ABB25437.1
annotation not available (431 aa)
   
 
    0.813
Your Current Organism:
Synechococcus sp. CC9902
NCBI taxonomy Id: 316279
Other names: S. sp. CC9902, Synechococcus sp. CC9902
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