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pykF protein (Escherichia coli K12 DH10B) - STRING interaction network
"pykF" - Pyruvate kinase in Escherichia coli K12 DH10B
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pykFPyruvate kinase (470 aa)    
Predicted Functional Partners:
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. It is also a component of the RNA degradosome, a multi-enzyme complex involved in RNA processing and messenger RNA degradation. Its interaction with RNase E is important for the turnover of mRNA, in particular on transcripts encoding enzymes of energy-generating metabolic routes. Its presence in the degradosome is required for the response to excess phosphosugar. May play a regulatory role in the degradation [...] (432 aa)
 
  0.999
pgi
Glucose-6-phosphate isomerase (549 aa)
   
 
  0.980
pgk
Phosphoglycerate kinase (387 aa)
 
 
  0.978
htpH
Fermentative D-lactate dehydrogenase, NAD-dependent; Fermentative lactate dehydrogenase (329 aa)
 
 
  0.977
pflB
Pyruvate formate lyase I (760 aa)
     
  0.975
pflD
Putative formate acetyltransferase 2 (765 aa)
     
  0.975
poxB
Pyruvate dehydrogenase (572 aa)
     
  0.975
ybiW
Pyruvate formate lyase (810 aa)
     
  0.975
fda
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (359 aa)
 
  0.971
dld
D-lactate dehydrogenase; First component of the membrane-bound D-lactate oxidase, which is believed to play an important role in the energization of the active transport of a variety of sugars and amino acids (571 aa)
   
  0.971
Your Current Organism:
Escherichia coli K12 DH10B
NCBI taxonomy Id: 316385
Other names: E. coli str. K-12 substr. DH10B, Escherichia coli DH10B, Escherichia coli K12 DH10B, Escherichia coli str. K-12 substr. DH10B, Escherichia coli str. K12 substr. DH10B, Escherichia coli strain K12 substrain DH10B
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