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yrfF protein (Escherichia coli K12 DH10B) - STRING interaction network
"yrfF" - Inner membrane protein in Escherichia coli K12 DH10B
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yrfFInner membrane protein (711 aa)    
Predicted Functional Partners:
rcsF
Outer membrane lipoprotein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects. The system controls expression of genes involved in colanic acid capsule synthesis, biofilm formation and cell division (134 aa)
   
 
 
  0.971
rcsC
Hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. RcsC has also phosphatase activity. The system controls expression of genes involved in colanic acid capsule synthesis, biofilm formation and cell division (949 aa)
   
     
  0.793
rffC
TDP-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4- amino-4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA) (224 aa)
   
     
  0.792
yiiQ
Hypothetical protein (199 aa)
   
          0.782
panM
Hypothetical protein; Acetyl-coenzyme A (CoA) sensor, which is involved in the conversion of inactive pro-PanD into active PanD. Binding of acetyl-CoA stimulates PanM activity, accelerating PanD cleavage by an acetylation-independent mechanism (127 aa)
   
          0.782
yebY
Hypothetical protein (113 aa)
   
          0.782
tomB
Hypothetical protein; Attenuates Hha toxicity and regulates biofilm formation. Binds to various coding and intergenic regions of genomic DNA (124 aa)
   
          0.782
rof
Rho-binding antiterminator; Suppresses temperature-sensitive mutations in essential genes by modulating rho-dependent transcription termination (84 aa)
   
          0.782
smp
Hypothetical protein (214 aa)
   
          0.781
yjeI
Hypothetical protein (117 aa)
   
          0.781
Your Current Organism:
Escherichia coli K12 DH10B
NCBI taxonomy Id: 316385
Other names: E. coli str. K-12 substr. DH10B, Escherichia coli DH10B, Escherichia coli K12 DH10B, Escherichia coli str. K-12 substr. DH10B, Escherichia coli str. K12 substr. DH10B, Escherichia coli strain K12 substrain DH10B
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