Genes that are sometimes fused into single open reading frames.
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Textmining
Automated, unsupervised textmining - searching for proteins that are frequently mentioned together.
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Coexpression
Proteins whose genes are observed to be correlated in expression, across a large number of experiments.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YlbG
annotation not available (123 aa)
Predicted Functional Partners:
YbbB
annotation not available
0.552
YrbL
annotation not available
0.501
YbbS
annotation not available
0.444
Your Current Organism:
Escherichia coli K12 W3110
NCBI taxonomy Id: 316407 Other names: E. coli str. K-12 substr. W3110, Escherichia coli K12 substr. W3110, Escherichia coli W3110, Escherichia coli str. K-12 substr. W3110, Escherichia coli str. K12 substr. W3110, Escherichia coli str. W3110, Escherichia coli strain W3110