node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tcr_0172 | Tcr_0174 | Tcr_0172 | Tcr_0174 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Conserved hypothetical protein with DUF81; PFAM: protein of unknown function DUF81; KEGG: tth:TTC0483 putative permease. | 0.456 |
Tcr_0172 | Tcr_0175 | Tcr_0172 | Tcr_0175 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | KEGG: bba:Bd1966 hypothetical protein. | 0.412 |
Tcr_0172 | Tcr_0191 | Tcr_0172 | Tcr_0191 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.420 |
Tcr_0172 | luxS | Tcr_0172 | Tcr_2129 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.957 |
Tcr_0172 | trmA | Tcr_0172 | Tcr_0173 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). | 0.495 |
Tcr_0174 | Tcr_0172 | Tcr_0174 | Tcr_0172 | Conserved hypothetical protein with DUF81; PFAM: protein of unknown function DUF81; KEGG: tth:TTC0483 putative permease. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.456 |
Tcr_0174 | Tcr_0175 | Tcr_0174 | Tcr_0175 | Conserved hypothetical protein with DUF81; PFAM: protein of unknown function DUF81; KEGG: tth:TTC0483 putative permease. | KEGG: bba:Bd1966 hypothetical protein. | 0.746 |
Tcr_0174 | trmA | Tcr_0174 | Tcr_0173 | Conserved hypothetical protein with DUF81; PFAM: protein of unknown function DUF81; KEGG: tth:TTC0483 putative permease. | tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). | 0.813 |
Tcr_0175 | Tcr_0172 | Tcr_0175 | Tcr_0172 | KEGG: bba:Bd1966 hypothetical protein. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.412 |
Tcr_0175 | Tcr_0174 | Tcr_0175 | Tcr_0174 | KEGG: bba:Bd1966 hypothetical protein. | Conserved hypothetical protein with DUF81; PFAM: protein of unknown function DUF81; KEGG: tth:TTC0483 putative permease. | 0.746 |
Tcr_0175 | trmA | Tcr_0175 | Tcr_0173 | KEGG: bba:Bd1966 hypothetical protein. | tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). | 0.746 |
Tcr_0191 | Tcr_0172 | Tcr_0191 | Tcr_0172 | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.420 |
Tcr_0191 | Tcr_1198 | Tcr_0191 | Tcr_1198 | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | SSU ribosomal protein S1P; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.635 |
Tcr_0191 | tmcA | Tcr_0191 | Tcr_2050 | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Conserved hypothetical protein with DUF699; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). | 0.663 |
Tcr_0191 | trmA | Tcr_0191 | Tcr_0173 | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). | 0.424 |
Tcr_0191 | trmB | Tcr_0191 | Tcr_0119 | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.542 |
Tcr_1198 | Tcr_0191 | Tcr_1198 | Tcr_0191 | SSU ribosomal protein S1P; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.635 |
Tcr_1198 | Tcr_1545 | Tcr_1198 | Tcr_1545 | SSU ribosomal protein S1P; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | Carbonic anhydrase, alpha family; PFAM: carbonic anhydrase; KEGG: ana:all2929 carbonic anhydrase. | 0.493 |
Tcr_1198 | tmcA | Tcr_1198 | Tcr_2050 | SSU ribosomal protein S1P; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | Conserved hypothetical protein with DUF699; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). | 0.976 |
Tcr_1198 | trmA | Tcr_1198 | Tcr_0173 | SSU ribosomal protein S1P; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). | 0.489 |