node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tcr_0244 | Tcr_0247 | Tcr_0244 | Tcr_0247 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | 0.961 |
Tcr_0244 | Tcr_0248 | Tcr_0244 | Tcr_0248 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | 0.972 |
Tcr_0244 | Tcr_2017 | Tcr_0244 | Tcr_2017 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: phosphoglucomutase/phosphomannomutase C terminal phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: vvy:VV1020 phosphoglucomutase. | 0.938 |
Tcr_0244 | eno | Tcr_0244 | Tcr_1260 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 0.951 |
Tcr_0244 | glk | Tcr_0244 | Tcr_0507 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Glucokinase; KEGG: gvi:gll1169 glucokinase; TIGRFAM: glucokinase; PFAM: Glucokinase; Belongs to the bacterial glucokinase family. | 0.868 |
Tcr_0244 | pfp | Tcr_0244 | Tcr_1583 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.934 |
Tcr_0244 | pgi | Tcr_0244 | Tcr_0608 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | PFAM: phosphoglucose isomerase (PGI); KEGG: aci:ACIAD0101 glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.979 |
Tcr_0244 | pgk | Tcr_0244 | Tcr_0246 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | PFAM: phosphoglycerate kinase; KEGG: mca:MCA2021 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.889 |
Tcr_0244 | tpiA | Tcr_0244 | Tcr_0815 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.937 |
Tcr_0244 | zwf | Tcr_0244 | Tcr_1214 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.772 |
Tcr_0247 | Tcr_0244 | Tcr_0247 | Tcr_0244 | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.961 |
Tcr_0247 | Tcr_0248 | Tcr_0247 | Tcr_0248 | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | 0.973 |
Tcr_0247 | Tcr_2017 | Tcr_0247 | Tcr_2017 | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: phosphoglucomutase/phosphomannomutase C terminal phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: vvy:VV1020 phosphoglucomutase. | 0.496 |
Tcr_0247 | eno | Tcr_0247 | Tcr_1260 | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 0.991 |
Tcr_0247 | pfp | Tcr_0247 | Tcr_1583 | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.928 |
Tcr_0247 | pgi | Tcr_0247 | Tcr_0608 | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | PFAM: phosphoglucose isomerase (PGI); KEGG: aci:ACIAD0101 glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.980 |
Tcr_0247 | pgk | Tcr_0247 | Tcr_0246 | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | PFAM: phosphoglycerate kinase; KEGG: mca:MCA2021 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.973 |
Tcr_0247 | tpiA | Tcr_0247 | Tcr_0815 | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.924 |
Tcr_0247 | zwf | Tcr_0247 | Tcr_1214 | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.882 |
Tcr_0248 | Tcr_0244 | Tcr_0248 | Tcr_0244 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.972 |