node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tcr_0866 | hrcA | Tcr_0866 | Tcr_0868 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.599 |
Tcr_0866 | nadK | Tcr_0866 | Tcr_0867 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.789 |
Tcr_0866 | ribB | Tcr_0866 | Tcr_1398 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.460 |
Tcr_1003 | Tcr_1400 | Tcr_1003 | Tcr_1400 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: biotin/lipoyl attachment FAD-dependent pyridine nucleotide-disulphide oxidoreductase pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: bbr:BB2538 dihydrolipoamide dehydrogenase. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.454 |
Tcr_1003 | nadE | Tcr_1003 | Tcr_1372 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: biotin/lipoyl attachment FAD-dependent pyridine nucleotide-disulphide oxidoreductase pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: bbr:BB2538 dihydrolipoamide dehydrogenase. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.584 |
Tcr_1003 | nadK | Tcr_1003 | Tcr_0867 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: biotin/lipoyl attachment FAD-dependent pyridine nucleotide-disulphide oxidoreductase pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: bbr:BB2538 dihydrolipoamide dehydrogenase. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.426 |
Tcr_1003 | ribB | Tcr_1003 | Tcr_1398 | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: biotin/lipoyl attachment FAD-dependent pyridine nucleotide-disulphide oxidoreductase pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: bbr:BB2538 dihydrolipoamide dehydrogenase. | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.479 |
Tcr_1400 | Tcr_1003 | Tcr_1400 | Tcr_1003 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: biotin/lipoyl attachment FAD-dependent pyridine nucleotide-disulphide oxidoreductase pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: bbr:BB2538 dihydrolipoamide dehydrogenase. | 0.454 |
Tcr_1400 | argA | Tcr_1400 | Tcr_0598 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | N-acetylglutamate synthase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase aspartate/glutamate/uridylate kinase; KEGG: pst:PSPTO0324 N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | 0.518 |
Tcr_1400 | hrcA | Tcr_1400 | Tcr_0868 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.454 |
Tcr_1400 | nadD | Tcr_1400 | Tcr_0484 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.779 |
Tcr_1400 | nadE | Tcr_1400 | Tcr_1372 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.622 |
Tcr_1400 | nadK | Tcr_1400 | Tcr_0867 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.455 |
Tcr_1400 | ribB | Tcr_1400 | Tcr_1398 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
argA | Tcr_1400 | Tcr_0598 | Tcr_1400 | N-acetylglutamate synthase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase aspartate/glutamate/uridylate kinase; KEGG: pst:PSPTO0324 N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.518 |
argA | nadK | Tcr_0598 | Tcr_0867 | N-acetylglutamate synthase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase aspartate/glutamate/uridylate kinase; KEGG: pst:PSPTO0324 N-acetylglutamate synthase; Belongs to the acetyltransferase family. ArgA subfamily. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.508 |
ffh | nadK | Tcr_0998 | Tcr_0867 | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the i [...] | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.546 |
hrcA | Tcr_0866 | Tcr_0868 | Tcr_0866 | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.599 |
hrcA | Tcr_1400 | Tcr_0868 | Tcr_1400 | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.454 |
hrcA | nadK | Tcr_0868 | Tcr_0867 | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.589 |