STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcr_1101KEGG: vpa:VP1011 isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type; Belongs to the monomeric-type IDH family. (739 aa)    
Predicted Functional Partners:
Tcr_1709
2-oxoacid:acceptor oxidoreductase, alpha subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase pyruvate flavodoxin/ferredoxin oxidoreductase-like; KEGG: gka:GK1301 2-oxoglutarate synthase(2-oxoglutarate-ferredoxin oxidoreductase) alpha subunit.
  
 
 0.985
Tcr_1710
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate enzyme-like TPP-binding; KEGG: pai:PAE1558 2-oxoacid ferredoxin oxidoreductase beta subunit.
  
 
 0.957
Tcr_1142
Aconitase; PFAM: aconitate hydratase-like aconitate hydratase 2; KEGG: ana:all1267 aconitate hydratase; Belongs to the aconitase/IPM isomerase family.
  
 
 0.943
Tcr_1957
PFAM: glutamine amidotransferase, class-II glutamate synthase, alpha subunit-like ferredoxin-dependent glutamate synthase glutamate synthase; KEGG: pst:PSPTO5123 glutamate synthase, large subunit.
     
 0.886
Tcr_1137
KEGG: pae:PA2629 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
  0.827
Tcr_1836
Glutamate dehydrogenase (NADP); PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: syn:slr0710 NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.812
argH
TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: pae:PA5263 argininosuccinate lyase.
     
 0.805
Tcr_0222
PFAM: aldehyde dehydrogenase; KEGG: tel:tlr0221 succinate-semialdehyde dehydrogenase (NADP+).
   
 
  0.804
Tcr_1887
PFAM: aldehyde dehydrogenase; KEGG: ana:all3556 succinate-semialdehyde dehydrogenase.
   
 
  0.804
Tcr_0729
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
    
  0.803
Your Current Organism:
Hydrogenovibrio crunogenus
NCBI taxonomy Id: 317025
Other names: H. crunogenus XCL-2, Hydrogenovibrio crunogenus XCL-2, Thiomicrospira crunogena XCL-2
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.