STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tcr_1672PFAM: ATP dependent DNA ligase; KEGG: msu:MS0939 ATP-dependent DNA ligase. (266 aa)    
Predicted Functional Partners:
Tcr_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.991
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.946
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
    
 0.911
Tcr_2052
TIGRFAM: exodeoxyribonuclease III exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: ilo:IL1451 exonuclease III.
  
 
 0.877
Tcr_0733
Signal peptidase I. Serine peptidase. MEROPS family S26A; KEGG: mca:MCA1465 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; Belongs to the peptidase S26 family.
    
 0.718
Tcr_0356
D-alpha,beta-D-heptose 1,7-bisphosphate phosphatase; TIGRFAM: histidinol-phosphate phosphatase family protein hydrolase, HAD-superfamily, subfamily IIIA; KEGG: ppu:PP0059 hypothetical protein.
   
 0.690
Tcr_1269
Conserved hypothetical protein with a helicase c2 domain; SMART: Helicase c2; KEGG: mca:MCA1991 ATP-dependent helicase, putative.
   
 
 0.631
Tcr_1673
TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; KEGG: mca:MCA0767 competence protein ComE, putative.
       0.598
Tcr_0024
PFAM: beta-lactamase-like RNA-metabolising metallo-beta-lactamase; KEGG: ppr:PBPRB1407 metallo-beta-lactamase family protein.
  
 0.584
Tcr_0859
impB/mucB/samB family protein; PFAM: UMUC-like DNA-repair protein; KEGG: ecs:ECs1679 UmuC protein.
   
 
 0.555
Your Current Organism:
Hydrogenovibrio crunogenus
NCBI taxonomy Id: 317025
Other names: H. crunogenus XCL-2, Hydrogenovibrio crunogenus XCL-2, Thiomicrospira crunogena XCL-2
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