STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepAPepA aminopeptidase. Metallo peptidase. MEROPS family M17; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (493 aa)    
Predicted Functional Partners:
Tcr_1485
TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: mca:MCA0774 aminopeptidase N.
  
 0.937
gshB
KEGG: ppr:PBPRB1479 putative Glutathione synthase; Ribosomal protein S6 modification enzyme; Belongs to the prokaryotic GSH synthase family.
   
 
 0.918
gshB-2
KEGG: mca:MCA2338 glutathione synthetase; TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase-like glutathione synthetase, ATP-binding; Belongs to the prokaryotic GSH synthase family.
   
 
 0.918
Tcr_1715
Gamma-glutamyltransferase 1. Threonine peptidase. MEROPS family T03; KEGG: cvi:CV1415 g-glutamyltransferase precursor; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase.
     
 0.910
Tcr_1824
TIGRFAM: glutamate--cysteine ligase; KEGG: cvi:CV4276 probable glutamate-cysteine ligase.
    
 0.904
Tcr_1749
PFAM: DNA polymerase III chi subunit, HolC; KEGG: yps:YPTB0530 DNA polymerase III, chi subunit.
  
  
 0.890
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.828
Tcr_1755
PFAM: aminotransferase, class I and II; KEGG: aci:ACIAD2574 aspartate aminotransferase A.
   
  0.818
Tcr_1542
PFAM: aminotransferase, class I and II; KEGG: bfs:BF0911 putative aminotransferase.
  
 
  0.803
Tcr_1750
Pilus retraction ATPase PilT; KEGG: son:SO3351 twitching motility protein PilT; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: ATPase.
       0.626
Your Current Organism:
Hydrogenovibrio crunogenus
NCBI taxonomy Id: 317025
Other names: H. crunogenus XCL-2, Hydrogenovibrio crunogenus XCL-2, Thiomicrospira crunogena XCL-2
Server load: low (28%) [HD]