node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Tcr_0247 | Tcr_0463 | Tcr_0247 | Tcr_0463 | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | Ribonucleoside-diphosphate reductase class Ia alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.907 |
Tcr_0247 | Tcr_1763 | Tcr_0247 | Tcr_1763 | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | PFAM: ribonucleotide reductase; KEGG: plu:plu3053 ribonucleoside-diphosphate reductase 1 beta chain (ribonucleotide reductase 1) (B2 protein) (R2 protein). | 0.911 |
Tcr_0247 | Tcr_2144 | Tcr_0247 | Tcr_2144 | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.903 |
Tcr_0247 | gmk | Tcr_0247 | Tcr_2138 | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.917 |
Tcr_0247 | guaA | Tcr_0247 | Tcr_1615 | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.508 |
Tcr_0247 | ndk | Tcr_0247 | Tcr_0619 | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.908 |
Tcr_0247 | rpoZ | Tcr_0247 | Tcr_2143 | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.628 |
Tcr_0463 | Tcr_0247 | Tcr_0463 | Tcr_0247 | Ribonucleoside-diphosphate reductase class Ia alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | 0.907 |
Tcr_0463 | Tcr_1763 | Tcr_0463 | Tcr_1763 | Ribonucleoside-diphosphate reductase class Ia alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | PFAM: ribonucleotide reductase; KEGG: plu:plu3053 ribonucleoside-diphosphate reductase 1 beta chain (ribonucleotide reductase 1) (B2 protein) (R2 protein). | 0.999 |
Tcr_0463 | Tcr_2144 | Tcr_0463 | Tcr_2144 | Ribonucleoside-diphosphate reductase class Ia alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |
Tcr_0463 | gmk | Tcr_0463 | Tcr_2138 | Ribonucleoside-diphosphate reductase class Ia alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.912 |
Tcr_0463 | guaA | Tcr_0463 | Tcr_1615 | Ribonucleoside-diphosphate reductase class Ia alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.592 |
Tcr_0463 | ndk | Tcr_0463 | Tcr_0619 | Ribonucleoside-diphosphate reductase class Ia alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.922 |
Tcr_1757 | apt | Tcr_1757 | Tcr_0108 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase; KEGG: pae:PA5177 probable hydrolase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.908 |
Tcr_1757 | gmk | Tcr_1757 | Tcr_2138 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase; KEGG: pae:PA5177 probable hydrolase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.900 |
Tcr_1757 | guaA | Tcr_1757 | Tcr_1615 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase; KEGG: pae:PA5177 probable hydrolase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.917 |
Tcr_1757 | surE | Tcr_1757 | Tcr_1257 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase-like hydrolase; KEGG: pae:PA5177 probable hydrolase. | 3'-nucleotidase / 5'-nucleotidase / exopolyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.909 |
Tcr_1763 | Tcr_0247 | Tcr_1763 | Tcr_0247 | PFAM: ribonucleotide reductase; KEGG: plu:plu3053 ribonucleoside-diphosphate reductase 1 beta chain (ribonucleotide reductase 1) (B2 protein) (R2 protein). | PFAM: pyruvate kinase; KEGG: vpa:VP2039 pyruvate kinase II; Belongs to the pyruvate kinase family. | 0.911 |
Tcr_1763 | Tcr_0463 | Tcr_1763 | Tcr_0463 | PFAM: ribonucleotide reductase; KEGG: plu:plu3053 ribonucleoside-diphosphate reductase 1 beta chain (ribonucleotide reductase 1) (B2 protein) (R2 protein). | Ribonucleoside-diphosphate reductase class Ia alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.999 |
Tcr_1763 | Tcr_2144 | Tcr_1763 | Tcr_2144 | PFAM: ribonucleotide reductase; KEGG: plu:plu3053 ribonucleoside-diphosphate reductase 1 beta chain (ribonucleotide reductase 1) (B2 protein) (R2 protein). | (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.900 |