STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sala_0629Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)    
Predicted Functional Partners:
Sala_0630
FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
  
 0.997
Sala_0145
Thioredoxin reductase.
  
 
 0.946
Sala_0343
Cyclic nucleotide-binding protein.
  
 
 0.931
Sala_0074
Thioredoxin-like protein.
  
 0.922
Sala_0166
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.912
Sala_0200
Thioredoxin domain 2.
  
 0.873
Sala_1515
Thioredoxin-like protein.
  
 0.873
Sala_2699
Hypothetical protein.
  
 0.873
fur
Ferric uptake regulator, Fur family; Belongs to the Fur family.
  
  
 0.748
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 0.672
Your Current Organism:
Sphingopyxis alaskensis
NCBI taxonomy Id: 317655
Other names: S. alaskensis RB2256, Sphingopyxis alaskensis RB2256, Sphingopyxis alaskensis str. RB2256, Sphingopyxis alaskensis strain RB2256
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