node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sala_0121 | Sala_1237 | Sala_0121 | Sala_1237 | Pyridine nucleotide-disulphide oxidoreductase dimerisation region. | Dihydrolipoamide dehydrogenase. | 0.926 |
Sala_0121 | Sala_1867 | Sala_0121 | Sala_1867 | Pyridine nucleotide-disulphide oxidoreductase dimerisation region. | Glycine dehydrogenase (decarboxylating) beta subunit. | 0.910 |
Sala_0121 | Sala_1871 | Sala_0121 | Sala_1871 | Pyridine nucleotide-disulphide oxidoreductase dimerisation region. | Glycine cleavage system T protein. | 0.938 |
Sala_0121 | Sala_2225 | Sala_0121 | Sala_2225 | Pyridine nucleotide-disulphide oxidoreductase dimerisation region. | Dihydrolipoamide dehydrogenase. | 0.925 |
Sala_0121 | gcvH | Sala_0121 | Sala_1870 | Pyridine nucleotide-disulphide oxidoreductase dimerisation region. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.951 |
Sala_0121 | gcvPA | Sala_0121 | Sala_1868 | Pyridine nucleotide-disulphide oxidoreductase dimerisation region. | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.909 |
Sala_0121 | glyA | Sala_0121 | Sala_0791 | Pyridine nucleotide-disulphide oxidoreductase dimerisation region. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.911 |
Sala_0496 | Sala_1206 | Sala_0496 | Sala_1206 | L-threonine aldolase. | 5-aminolevulinate synthase. | 0.908 |
Sala_0496 | Sala_1845 | Sala_0496 | Sala_1845 | L-threonine aldolase. | FAD dependent oxidoreductase. | 0.905 |
Sala_0496 | Sala_1867 | Sala_0496 | Sala_1867 | L-threonine aldolase. | Glycine dehydrogenase (decarboxylating) beta subunit. | 0.919 |
Sala_0496 | gcvPA | Sala_0496 | Sala_1868 | L-threonine aldolase. | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.919 |
Sala_0496 | glyA | Sala_0496 | Sala_0791 | L-threonine aldolase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.940 |
Sala_1206 | Sala_0496 | Sala_1206 | Sala_0496 | 5-aminolevulinate synthase. | L-threonine aldolase. | 0.908 |
Sala_1206 | Sala_1845 | Sala_1206 | Sala_1845 | 5-aminolevulinate synthase. | FAD dependent oxidoreductase. | 0.906 |
Sala_1206 | Sala_1867 | Sala_1206 | Sala_1867 | 5-aminolevulinate synthase. | Glycine dehydrogenase (decarboxylating) beta subunit. | 0.912 |
Sala_1206 | Sala_1871 | Sala_1206 | Sala_1871 | 5-aminolevulinate synthase. | Glycine cleavage system T protein. | 0.414 |
Sala_1206 | gcvPA | Sala_1206 | Sala_1868 | 5-aminolevulinate synthase. | Glycine dehydrogenase (decarboxylating) alpha subunit; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.910 |
Sala_1206 | glyA | Sala_1206 | Sala_0791 | 5-aminolevulinate synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.922 |
Sala_1237 | Sala_0121 | Sala_1237 | Sala_0121 | Dihydrolipoamide dehydrogenase. | Pyridine nucleotide-disulphide oxidoreductase dimerisation region. | 0.926 |
Sala_1237 | Sala_1867 | Sala_1237 | Sala_1867 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating) beta subunit. | 0.925 |