node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sfri_0002 | Sfri_0452 | Sfri_0002 | Sfri_0452 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | 0.896 |
Sfri_0002 | Sfri_1924 | Sfri_0002 | Sfri_1924 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO2380 RecQ domain protein. | 0.591 |
Sfri_0002 | Sfri_3657 | Sfri_0002 | Sfri_3657 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: NERD domain protein; KEGG: pha:PSHAb0100 putative orphan protein. | 0.591 |
Sfri_0002 | Sfri_3822 | Sfri_0002 | Sfri_3822 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO4241 ATP-dependent DNA helicase RecQ. | 0.591 |
Sfri_0002 | mutL | Sfri_0002 | Sfri_3313 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.920 |
Sfri_0002 | mutS | Sfri_0002 | Sfri_1061 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.984 |
Sfri_0002 | polA | Sfri_0002 | Sfri_3943 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.993 |
Sfri_0002 | xni | Sfri_0002 | Sfri_2776 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 5'-3' exonuclease; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.969 |
Sfri_0452 | Sfri_0002 | Sfri_0452 | Sfri_0002 | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.896 |
Sfri_0452 | Sfri_1924 | Sfri_0452 | Sfri_1924 | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO2380 RecQ domain protein. | 0.911 |
Sfri_0452 | Sfri_3657 | Sfri_0452 | Sfri_3657 | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | PFAM: NERD domain protein; KEGG: pha:PSHAb0100 putative orphan protein. | 0.911 |
Sfri_0452 | Sfri_3822 | Sfri_0452 | Sfri_3822 | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO4241 ATP-dependent DNA helicase RecQ. | 0.911 |
Sfri_0452 | mutL | Sfri_0452 | Sfri_3313 | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.898 |
Sfri_0452 | mutS | Sfri_0452 | Sfri_1061 | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.510 |
Sfri_0452 | polA | Sfri_0452 | Sfri_3943 | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.744 |
Sfri_0452 | xni | Sfri_0452 | Sfri_2776 | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | 5'-3' exonuclease; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.589 |
Sfri_1924 | Sfri_0002 | Sfri_1924 | Sfri_0002 | TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO2380 RecQ domain protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.591 |
Sfri_1924 | Sfri_0452 | Sfri_1924 | Sfri_0452 | TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO2380 RecQ domain protein. | PFAM: UvrD/REP helicase; DNA topoisomerase, type IA, zn finger domain protein; KEGG: cps:CPS_2454 helicase IV. | 0.911 |
Sfri_1924 | Sfri_3822 | Sfri_1924 | Sfri_3822 | TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO2380 RecQ domain protein. | TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO4241 ATP-dependent DNA helicase RecQ. | 0.920 |
Sfri_1924 | mutL | Sfri_1924 | Sfri_3313 | TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; KEGG: son:SO2380 RecQ domain protein. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.863 |