node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sfri_0229 | Sfri_0456 | Sfri_0229 | Sfri_0456 | PFAM: fumarate lyase; KEGG: vch:VC1573 fumarate hydratase, class II. | KEGG: son:SO0396 fumarate reductase cytochrome B subunit. | 0.947 |
Sfri_0229 | Sfri_0457 | Sfri_0229 | Sfri_0457 | PFAM: fumarate lyase; KEGG: vch:VC1573 fumarate hydratase, class II. | KEGG: son:SO0398 fumarate reductase flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. | 0.956 |
Sfri_0229 | Sfri_0458 | Sfri_0229 | Sfri_0458 | PFAM: fumarate lyase; KEGG: vch:VC1573 fumarate hydratase, class II. | Succinate dehydrogenase subunit B; KEGG: son:SO0399 fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.951 |
Sfri_0229 | Sfri_0678 | Sfri_0229 | Sfri_0678 | PFAM: fumarate lyase; KEGG: vch:VC1573 fumarate hydratase, class II. | Succinate dehydrogenase subunit B; KEGG: son:SO0399 fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.951 |
Sfri_0229 | Sfri_0679 | Sfri_0229 | Sfri_0679 | PFAM: fumarate lyase; KEGG: vch:VC1573 fumarate hydratase, class II. | KEGG: son:SO0398 fumarate reductase flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. | 0.959 |
Sfri_0229 | Sfri_0680 | Sfri_0229 | Sfri_0680 | PFAM: fumarate lyase; KEGG: vch:VC1573 fumarate hydratase, class II. | KEGG: son:SO0396 fumarate reductase cytochrome B subunit. | 0.947 |
Sfri_0229 | Sfri_2156 | Sfri_0229 | Sfri_2156 | PFAM: fumarate lyase; KEGG: vch:VC1573 fumarate hydratase, class II. | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.969 |
Sfri_0229 | fccA | Sfri_0229 | Sfri_3690 | PFAM: fumarate lyase; KEGG: vch:VC1573 fumarate hydratase, class II. | Flavocytochrome c; Catalyzes fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown, but evidence indicates that flavocytochrome c participates in electron transfer from formate to fumarate and possibly also to trimethylamine oxide (TMAO). This enzyme is essentially unidirectional (By similarity); In the C-terminal section; belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.954 |
Sfri_0229 | sucC | Sfri_0229 | Sfri_2341 | PFAM: fumarate lyase; KEGG: vch:VC1573 fumarate hydratase, class II. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.659 |
Sfri_0229 | sucD | Sfri_0229 | Sfri_2340 | PFAM: fumarate lyase; KEGG: vch:VC1573 fumarate hydratase, class II. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.757 |
Sfri_0456 | Sfri_0229 | Sfri_0456 | Sfri_0229 | KEGG: son:SO0396 fumarate reductase cytochrome B subunit. | PFAM: fumarate lyase; KEGG: vch:VC1573 fumarate hydratase, class II. | 0.947 |
Sfri_0456 | Sfri_0457 | Sfri_0456 | Sfri_0457 | KEGG: son:SO0396 fumarate reductase cytochrome B subunit. | KEGG: son:SO0398 fumarate reductase flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. | 0.998 |
Sfri_0456 | Sfri_0458 | Sfri_0456 | Sfri_0458 | KEGG: son:SO0396 fumarate reductase cytochrome B subunit. | Succinate dehydrogenase subunit B; KEGG: son:SO0399 fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.999 |
Sfri_0456 | Sfri_0678 | Sfri_0456 | Sfri_0678 | KEGG: son:SO0396 fumarate reductase cytochrome B subunit. | Succinate dehydrogenase subunit B; KEGG: son:SO0399 fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.998 |
Sfri_0456 | Sfri_0679 | Sfri_0456 | Sfri_0679 | KEGG: son:SO0396 fumarate reductase cytochrome B subunit. | KEGG: son:SO0398 fumarate reductase flavoprotein subunit; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. | 0.993 |
Sfri_0456 | Sfri_0680 | Sfri_0456 | Sfri_0680 | KEGG: son:SO0396 fumarate reductase cytochrome B subunit. | KEGG: son:SO0396 fumarate reductase cytochrome B subunit. | 0.902 |
Sfri_0456 | Sfri_2156 | Sfri_0456 | Sfri_2156 | KEGG: son:SO0396 fumarate reductase cytochrome B subunit. | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.972 |
Sfri_0456 | fccA | Sfri_0456 | Sfri_3690 | KEGG: son:SO0396 fumarate reductase cytochrome B subunit. | Flavocytochrome c; Catalyzes fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown, but evidence indicates that flavocytochrome c participates in electron transfer from formate to fumarate and possibly also to trimethylamine oxide (TMAO). This enzyme is essentially unidirectional (By similarity); In the C-terminal section; belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.974 |
Sfri_0456 | sucC | Sfri_0456 | Sfri_2341 | KEGG: son:SO0396 fumarate reductase cytochrome B subunit. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.941 |
Sfri_0456 | sucD | Sfri_0456 | Sfri_2340 | KEGG: son:SO0396 fumarate reductase cytochrome B subunit. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.925 |