STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gfaGlutathione-dependent formaldehyde-activating, GFA; Catalyzes the condensation of formaldehyde and glutathione to S-hydroxymethylglutathione; Belongs to the Gfa family. (194 aa)    
Predicted Functional Partners:
Pden_0016
PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: rsp:RSP_2576 alcohol dehydrogenase class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
    
 0.971
fghA
Carboxylesterase; Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate (Probable).
    
 0.970
Pden_0020
PFAM: Pyrrolo-quinoline quinone; KEGG: rsp:RSP_2578 putative pqq dehydrogenase protein.
 
 
 0.958
Pden_2993
PFAM: Pyrrolo-quinoline quinone; KEGG: rpe:RPE_3139 pyrrolo-quinoline quinone.
 
 
 0.931
Pden_2994
Amino acid ABC transporter substrate-binding protein, PAAT family; SMART: extracellular solute-binding protein, family 3; KEGG: rpc:RPC_1908 extracellular solute-binding protein, family 3; TC 3.A.1.3.-.
 
  
 0.920
Pden_1186
Glutathione-independent formaldehyde dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: atc:AGR_C_2885 hypothetical protein.
   
 
  0.900
Pden_1703
KEGG: pfo:Pfl_2975 quinohemoprotein amine dehydrogenase, 60 kDa subunit.
     
 0.900
Pden_2995
Cytochrome c, class I; Electron acceptor for MDH. Acts in methanol oxidation.
     
 0.900
Pden_2996
Methanol dehydrogenase, beta subunit; Catalyzes the oxidation of primary alcohols including methanol.
     
  0.900
Pden_2999
KEGG: rpc:RPC_1913 MxaA protein, putative.
     
  0.900
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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