node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pden_0584 | Pden_0585 | Pden_0584 | Pden_0585 | KEGG: sil:SPO1180 hypothetical protein. | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: rsp:RSP_2098 cell division protein FtsI/penicillin-binding protein 2. | 0.878 |
Pden_0584 | mraY | Pden_0584 | Pden_0588 | KEGG: sil:SPO1180 hypothetical protein. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.810 |
Pden_0584 | mraZ | Pden_0584 | Pden_0582 | KEGG: sil:SPO1180 hypothetical protein. | PFAM: protein of unknown function UPF0040; KEGG: rde:RD1_3370 MraZ protein, putative; Belongs to the MraZ family. | 0.868 |
Pden_0584 | murD | Pden_0584 | Pden_0589 | KEGG: sil:SPO1180 hypothetical protein. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.738 |
Pden_0584 | murE | Pden_0584 | Pden_0586 | KEGG: sil:SPO1180 hypothetical protein. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.810 |
Pden_0584 | murF | Pden_0584 | Pden_0587 | KEGG: sil:SPO1180 hypothetical protein. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.734 |
Pden_0584 | rsmH | Pden_0584 | Pden_0583 | KEGG: sil:SPO1180 hypothetical protein. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.883 |
Pden_0585 | Pden_0584 | Pden_0585 | Pden_0584 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: rsp:RSP_2098 cell division protein FtsI/penicillin-binding protein 2. | KEGG: sil:SPO1180 hypothetical protein. | 0.878 |
Pden_0585 | mraY | Pden_0585 | Pden_0588 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: rsp:RSP_2098 cell division protein FtsI/penicillin-binding protein 2. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.934 |
Pden_0585 | mraZ | Pden_0585 | Pden_0582 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: rsp:RSP_2098 cell division protein FtsI/penicillin-binding protein 2. | PFAM: protein of unknown function UPF0040; KEGG: rde:RD1_3370 MraZ protein, putative; Belongs to the MraZ family. | 0.947 |
Pden_0585 | murD | Pden_0585 | Pden_0589 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: rsp:RSP_2098 cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.943 |
Pden_0585 | murE | Pden_0585 | Pden_0586 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: rsp:RSP_2098 cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.991 |
Pden_0585 | murF | Pden_0585 | Pden_0587 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: rsp:RSP_2098 cell division protein FtsI/penicillin-binding protein 2. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.938 |
Pden_0585 | rsmH | Pden_0585 | Pden_0583 | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: rsp:RSP_2098 cell division protein FtsI/penicillin-binding protein 2. | S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.941 |
mraY | Pden_0584 | Pden_0588 | Pden_0584 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | KEGG: sil:SPO1180 hypothetical protein. | 0.810 |
mraY | Pden_0585 | Pden_0588 | Pden_0585 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: rsp:RSP_2098 cell division protein FtsI/penicillin-binding protein 2. | 0.934 |
mraY | mraZ | Pden_0588 | Pden_0582 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | PFAM: protein of unknown function UPF0040; KEGG: rde:RD1_3370 MraZ protein, putative; Belongs to the MraZ family. | 0.810 |
mraY | murD | Pden_0588 | Pden_0589 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.987 |
mraY | murE | Pden_0588 | Pden_0586 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.987 |
mraY | murF | Pden_0588 | Pden_0587 | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.998 |