node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pden_0692 | htpX | Pden_0692 | Pden_0694 | Hypothetical protein; TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: rde:RD1_2106 hypothetical protein. | Heat shock protein, Metallo peptidase, MEROPS family M48B; PFAM: peptidase M48, Ste24p; KEGG: rsp:RSP_0554 heat shock protein HtpX; Belongs to the peptidase M48B family. | 0.780 |
Pden_0692 | ruvA | Pden_0692 | Pden_0695 | Hypothetical protein; TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: rde:RD1_2106 hypothetical protein. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.788 |
Pden_0692 | ruvB | Pden_0692 | Pden_0693 | Hypothetical protein; TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: rde:RD1_2106 hypothetical protein. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.781 |
Pden_0692 | ruvC | Pden_0692 | Pden_0696 | Hypothetical protein; TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: rde:RD1_2106 hypothetical protein. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.774 |
Pden_4082 | pheT | Pden_4082 | Pden_2262 | PFAM: helicase domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: rsp:RSP_2623N haem peroxidase. | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: sil:SPO3489 phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.467 |
Pden_4082 | polA | Pden_4082 | Pden_1853 | PFAM: helicase domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: rsp:RSP_2623N haem peroxidase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.761 |
Pden_4082 | recF | Pden_4082 | Pden_2835 | PFAM: helicase domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: rsp:RSP_2623N haem peroxidase. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.706 |
Pden_4082 | recR | Pden_4082 | Pden_3647 | PFAM: helicase domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: rsp:RSP_2623N haem peroxidase. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.649 |
Pden_4082 | ruvA | Pden_4082 | Pden_0695 | PFAM: helicase domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: rsp:RSP_2623N haem peroxidase. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.711 |
Pden_4082 | ruvB | Pden_4082 | Pden_0693 | PFAM: helicase domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: rsp:RSP_2623N haem peroxidase. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.612 |
Pden_4082 | ruvC | Pden_4082 | Pden_0696 | PFAM: helicase domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: rsp:RSP_2623N haem peroxidase. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.633 |
htpX | Pden_0692 | Pden_0694 | Pden_0692 | Heat shock protein, Metallo peptidase, MEROPS family M48B; PFAM: peptidase M48, Ste24p; KEGG: rsp:RSP_0554 heat shock protein HtpX; Belongs to the peptidase M48B family. | Hypothetical protein; TIGRFAM: uncharacterized domain 1; PFAM: thioesterase superfamily protein; KEGG: rde:RD1_2106 hypothetical protein. | 0.780 |
htpX | ruvA | Pden_0694 | Pden_0695 | Heat shock protein, Metallo peptidase, MEROPS family M48B; PFAM: peptidase M48, Ste24p; KEGG: rsp:RSP_0554 heat shock protein HtpX; Belongs to the peptidase M48B family. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.795 |
htpX | ruvB | Pden_0694 | Pden_0693 | Heat shock protein, Metallo peptidase, MEROPS family M48B; PFAM: peptidase M48, Ste24p; KEGG: rsp:RSP_0554 heat shock protein HtpX; Belongs to the peptidase M48B family. | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.794 |
htpX | ruvC | Pden_0694 | Pden_0696 | Heat shock protein, Metallo peptidase, MEROPS family M48B; PFAM: peptidase M48, Ste24p; KEGG: rsp:RSP_0554 heat shock protein HtpX; Belongs to the peptidase M48B family. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.788 |
pheT | Pden_4082 | Pden_2262 | Pden_4082 | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: sil:SPO3489 phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | PFAM: helicase domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: rsp:RSP_2623N haem peroxidase. | 0.467 |
pheT | polA | Pden_2262 | Pden_1853 | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: sil:SPO3489 phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.881 |
pheT | recF | Pden_2262 | Pden_2835 | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: sil:SPO3489 phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.686 |
pheT | recR | Pden_2262 | Pden_3647 | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: sil:SPO3489 phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.597 |
pheT | ruvA | Pden_2262 | Pden_0695 | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: sil:SPO3489 phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.734 |