STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pden_0927KEGG: rsp:RSP_2659 deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: putative deoxyguanosinetriphosphate triphosphohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; Belongs to the dGTPase family. Type 2 subfamily. (378 aa)    
Predicted Functional Partners:
surE
3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.912
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
 
  0.903
Pden_0524
Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
  0.902
Pden_2989
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; KEGG: rru:Rru_A1276 ATP-cone.
    
  0.901
Pden_2276
PFAM: pyruvate kinase; KEGG: sil:SPO3600 pyruvate kinase; Belongs to the pyruvate kinase family.
     
  0.900
Pden_2882
PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: sit:TM1040_1548 5'-nucleotidase-like; Belongs to the 5'-nucleotidase family.
     
  0.900
Pden_0928
TIGRFAM: iron-sulfur cluster assembly accessory protein; PFAM: HesB/YadR/YfhF-family protein; KEGG: jan:Jann_1504 HesB/YadR/YfhF; Belongs to the HesB/IscA family.
     
 0.784
Pden_0929
TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: rsp:RSP_2657 exodeoxyribonuclease III.
       0.599
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
   
 0.493
Pden_1579
KEGG: rde:RD1_1243 nicotinate (nicotinamide) nucleotide adenylyltransferase, putative; TIGRFAM: cytidyltransferase-related domain; nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase.
  
   
 0.493
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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