node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pden_0286 | Pden_0943 | Pden_0286 | Pden_0943 | PFAM: ornithine cyclodeaminase/mu-crystallin; Shikimate/quinate 5-dehydrogenase; KEGG: sme:SMb20433 putative cyclodeaminase protein. | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.944 |
Pden_0286 | Pden_1045 | Pden_0286 | Pden_1045 | PFAM: ornithine cyclodeaminase/mu-crystallin; Shikimate/quinate 5-dehydrogenase; KEGG: sme:SMb20433 putative cyclodeaminase protein. | PFAM: proline racemase; KEGG: rha:RHA1_ro05288 probable proline racemase; Belongs to the proline racemase family. | 0.929 |
Pden_0286 | Pden_1162 | Pden_0286 | Pden_1162 | PFAM: ornithine cyclodeaminase/mu-crystallin; Shikimate/quinate 5-dehydrogenase; KEGG: sme:SMb20433 putative cyclodeaminase protein. | PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: csa:Csal_1087 arginase/agmatinase/formiminoglutamase; Belongs to the arginase family. | 0.913 |
Pden_0286 | Pden_1185 | Pden_0286 | Pden_1185 | PFAM: ornithine cyclodeaminase/mu-crystallin; Shikimate/quinate 5-dehydrogenase; KEGG: sme:SMb20433 putative cyclodeaminase protein. | Ornithine cyclodeaminase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline, which would allow P.denitrificans to grow on t3LHyp as a sole carbon source. Belongs to the ornithine cyclodeaminase/mu-crystallin family. | 0.928 |
Pden_0286 | Pden_2047 | Pden_0286 | Pden_2047 | PFAM: ornithine cyclodeaminase/mu-crystallin; Shikimate/quinate 5-dehydrogenase; KEGG: sme:SMb20433 putative cyclodeaminase protein. | Arginase; TIGRFAM: arginase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: rsp:RSP_2632 arginase; Belongs to the arginase family. | 0.929 |
Pden_0286 | Pden_2321 | Pden_0286 | Pden_2321 | PFAM: ornithine cyclodeaminase/mu-crystallin; Shikimate/quinate 5-dehydrogenase; KEGG: sme:SMb20433 putative cyclodeaminase protein. | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: rsp:RSP_1991 putative ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.916 |
Pden_0286 | bhcD | Pden_0286 | Pden_3918 | PFAM: ornithine cyclodeaminase/mu-crystallin; Shikimate/quinate 5-dehydrogenase; KEGG: sme:SMb20433 putative cyclodeaminase protein. | Ornithine cyclodeaminase; Imine reductase that catalyzes the NADH-dependent reduction of iminosuccinate to L-aspartate. Is essential for the growth of P.denitrificans in the presence of glycolate and glyoxylate since it functions in glyoxylate assimilation via the beta-hydroxyaspartate cycle (BHAC). Thereby BhcD regenerates the amino group donor for the first step of the BHAC. | 0.924 |
Pden_0286 | proC | Pden_0286 | Pden_1192 | PFAM: ornithine cyclodeaminase/mu-crystallin; Shikimate/quinate 5-dehydrogenase; KEGG: sme:SMb20433 putative cyclodeaminase protein. | NADP oxidoreductase, coenzyme F420-dependent; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.911 |
Pden_0286 | proC-2 | Pden_0286 | Pden_2198 | PFAM: ornithine cyclodeaminase/mu-crystallin; Shikimate/quinate 5-dehydrogenase; KEGG: sme:SMb20433 putative cyclodeaminase protein. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.911 |
Pden_0943 | Pden_0286 | Pden_0943 | Pden_0286 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | PFAM: ornithine cyclodeaminase/mu-crystallin; Shikimate/quinate 5-dehydrogenase; KEGG: sme:SMb20433 putative cyclodeaminase protein. | 0.944 |
Pden_0943 | Pden_1045 | Pden_0943 | Pden_1045 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | PFAM: proline racemase; KEGG: rha:RHA1_ro05288 probable proline racemase; Belongs to the proline racemase family. | 0.907 |
Pden_0943 | Pden_1162 | Pden_0943 | Pden_1162 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: csa:Csal_1087 arginase/agmatinase/formiminoglutamase; Belongs to the arginase family. | 0.535 |
Pden_0943 | Pden_1185 | Pden_0943 | Pden_1185 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Ornithine cyclodeaminase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline, which would allow P.denitrificans to grow on t3LHyp as a sole carbon source. Belongs to the ornithine cyclodeaminase/mu-crystallin family. | 0.944 |
Pden_0943 | Pden_2047 | Pden_0943 | Pden_2047 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Arginase; TIGRFAM: arginase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: rsp:RSP_2632 arginase; Belongs to the arginase family. | 0.535 |
Pden_0943 | bhcD | Pden_0943 | Pden_3918 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Ornithine cyclodeaminase; Imine reductase that catalyzes the NADH-dependent reduction of iminosuccinate to L-aspartate. Is essential for the growth of P.denitrificans in the presence of glycolate and glyoxylate since it functions in glyoxylate assimilation via the beta-hydroxyaspartate cycle (BHAC). Thereby BhcD regenerates the amino group donor for the first step of the BHAC. | 0.944 |
Pden_0943 | proC | Pden_0943 | Pden_1192 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | NADP oxidoreductase, coenzyme F420-dependent; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.956 |
Pden_0943 | proC-2 | Pden_0943 | Pden_2198 | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.956 |
Pden_1045 | Pden_0286 | Pden_1045 | Pden_0286 | PFAM: proline racemase; KEGG: rha:RHA1_ro05288 probable proline racemase; Belongs to the proline racemase family. | PFAM: ornithine cyclodeaminase/mu-crystallin; Shikimate/quinate 5-dehydrogenase; KEGG: sme:SMb20433 putative cyclodeaminase protein. | 0.929 |
Pden_1045 | Pden_0943 | Pden_1045 | Pden_0943 | PFAM: proline racemase; KEGG: rha:RHA1_ro05288 probable proline racemase; Belongs to the proline racemase family. | L-proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.907 |
Pden_1045 | Pden_1185 | Pden_1045 | Pden_1185 | PFAM: proline racemase; KEGG: rha:RHA1_ro05288 probable proline racemase; Belongs to the proline racemase family. | Ornithine cyclodeaminase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using preferentially NADPH over NADH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L-proline (t3LHyp) to L-proline, which would allow P.denitrificans to grow on t3LHyp as a sole carbon source. Belongs to the ornithine cyclodeaminase/mu-crystallin family. | 0.956 |