node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pden_1045 | Pden_1197 | Pden_1045 | Pden_1197 | PFAM: proline racemase; KEGG: rha:RHA1_ro05288 probable proline racemase; Belongs to the proline racemase family. | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ppu:PP_4753 N-methylproline demethylase, putative. | 0.660 |
Pden_1045 | hpbD | Pden_1045 | Pden_1187 | PFAM: proline racemase; KEGG: rha:RHA1_ro05288 probable proline racemase; Belongs to the proline racemase family. | Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Catalyzes the 2-epimerization of trans-4-hydroxy-L-proline betaine (tHyp-B) to cis-4-hydroxy-D-proline betaine (cHyp-B). Is involved in a catabolic pathway that degrades tHyp-B to alpha- ketoglutarate. This pathway would permit the utilization of tHyp-B as a carbon and nitrogen source in the absence of osmotic stress, since tHyp-B functions as an osmolyte and is not catabolized when it is needed as osmoprotectant. Can also catalyze the racemization of L- proline betaine. | 0.694 |
Pden_1045 | proB | Pden_1045 | Pden_4055 | PFAM: proline racemase; KEGG: rha:RHA1_ro05288 probable proline racemase; Belongs to the proline racemase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.437 |
Pden_1175 | Pden_1176 | Pden_1175 | Pden_1176 | PFAM: Muconolactone delta-isomerase; KEGG: bam:Bamb_6586 muconolactone delta-isomerase. | TIGRFAM: catechol 1,2-dioxygenase; PFAM: intradiol ring-cleavage dioxygenase; Catechol dioxygenase, N-terminal domain protein; KEGG: aci:ACIAD1442 catechol 1,2-dioxygenase. | 0.981 |
Pden_1175 | Pden_1188 | Pden_1175 | Pden_1188 | PFAM: Muconolactone delta-isomerase; KEGG: bam:Bamb_6586 muconolactone delta-isomerase. | PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sme:SMa0752 possible dioxygenase reductase subunit. | 0.542 |
Pden_1175 | hpbD | Pden_1175 | Pden_1187 | PFAM: Muconolactone delta-isomerase; KEGG: bam:Bamb_6586 muconolactone delta-isomerase. | Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Catalyzes the 2-epimerization of trans-4-hydroxy-L-proline betaine (tHyp-B) to cis-4-hydroxy-D-proline betaine (cHyp-B). Is involved in a catabolic pathway that degrades tHyp-B to alpha- ketoglutarate. This pathway would permit the utilization of tHyp-B as a carbon and nitrogen source in the absence of osmotic stress, since tHyp-B functions as an osmolyte and is not catabolized when it is needed as osmoprotectant. Can also catalyze the racemization of L- proline betaine. | 0.697 |
Pden_1176 | Pden_1175 | Pden_1176 | Pden_1175 | TIGRFAM: catechol 1,2-dioxygenase; PFAM: intradiol ring-cleavage dioxygenase; Catechol dioxygenase, N-terminal domain protein; KEGG: aci:ACIAD1442 catechol 1,2-dioxygenase. | PFAM: Muconolactone delta-isomerase; KEGG: bam:Bamb_6586 muconolactone delta-isomerase. | 0.981 |
Pden_1176 | hpbD | Pden_1176 | Pden_1187 | TIGRFAM: catechol 1,2-dioxygenase; PFAM: intradiol ring-cleavage dioxygenase; Catechol dioxygenase, N-terminal domain protein; KEGG: aci:ACIAD1442 catechol 1,2-dioxygenase. | Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Catalyzes the 2-epimerization of trans-4-hydroxy-L-proline betaine (tHyp-B) to cis-4-hydroxy-D-proline betaine (cHyp-B). Is involved in a catabolic pathway that degrades tHyp-B to alpha- ketoglutarate. This pathway would permit the utilization of tHyp-B as a carbon and nitrogen source in the absence of osmotic stress, since tHyp-B functions as an osmolyte and is not catabolized when it is needed as osmoprotectant. Can also catalyze the racemization of L- proline betaine. | 0.725 |
Pden_1184 | Pden_1197 | Pden_1184 | Pden_1197 | Proline racemase; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts t3LHyp to L-proline, which would allow P.denitrificans to grow on t3LHyp as a sole carbon source. Displays neither proline racemase activity nor 4-hydroxyproline 2-epimerase activity. | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ppu:PP_4753 N-methylproline demethylase, putative. | 0.660 |
Pden_1184 | hpbD | Pden_1184 | Pden_1187 | Proline racemase; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts t3LHyp to L-proline, which would allow P.denitrificans to grow on t3LHyp as a sole carbon source. Displays neither proline racemase activity nor 4-hydroxyproline 2-epimerase activity. | Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Catalyzes the 2-epimerization of trans-4-hydroxy-L-proline betaine (tHyp-B) to cis-4-hydroxy-D-proline betaine (cHyp-B). Is involved in a catabolic pathway that degrades tHyp-B to alpha- ketoglutarate. This pathway would permit the utilization of tHyp-B as a carbon and nitrogen source in the absence of osmotic stress, since tHyp-B functions as an osmolyte and is not catabolized when it is needed as osmoprotectant. Can also catalyze the racemization of L- proline betaine. | 0.705 |
Pden_1184 | proB | Pden_1184 | Pden_4055 | Proline racemase; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Is likely involved in a degradation pathway that converts t3LHyp to L-proline, which would allow P.denitrificans to grow on t3LHyp as a sole carbon source. Displays neither proline racemase activity nor 4-hydroxyproline 2-epimerase activity. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.437 |
Pden_1186 | Pden_1188 | Pden_1186 | Pden_1188 | Glutathione-independent formaldehyde dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: atc:AGR_C_2885 hypothetical protein. | PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sme:SMa0752 possible dioxygenase reductase subunit. | 0.632 |
Pden_1186 | Pden_1189 | Pden_1186 | Pden_1189 | Glutathione-independent formaldehyde dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: atc:AGR_C_2885 hypothetical protein. | PFAM: Rieske [2Fe-2S] domain protein; KEGG: sme:SMa0751 putative aromatic-ring hydroxylating dioxygenase, alpha-subunit. | 0.651 |
Pden_1186 | hpbD | Pden_1186 | Pden_1187 | Glutathione-independent formaldehyde dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: atc:AGR_C_2885 hypothetical protein. | Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Catalyzes the 2-epimerization of trans-4-hydroxy-L-proline betaine (tHyp-B) to cis-4-hydroxy-D-proline betaine (cHyp-B). Is involved in a catabolic pathway that degrades tHyp-B to alpha- ketoglutarate. This pathway would permit the utilization of tHyp-B as a carbon and nitrogen source in the absence of osmotic stress, since tHyp-B functions as an osmolyte and is not catabolized when it is needed as osmoprotectant. Can also catalyze the racemization of L- proline betaine. | 0.706 |
Pden_1188 | Pden_1175 | Pden_1188 | Pden_1175 | PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sme:SMa0752 possible dioxygenase reductase subunit. | PFAM: Muconolactone delta-isomerase; KEGG: bam:Bamb_6586 muconolactone delta-isomerase. | 0.542 |
Pden_1188 | Pden_1186 | Pden_1188 | Pden_1186 | PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sme:SMa0752 possible dioxygenase reductase subunit. | Glutathione-independent formaldehyde dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: atc:AGR_C_2885 hypothetical protein. | 0.632 |
Pden_1188 | Pden_1189 | Pden_1188 | Pden_1189 | PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sme:SMa0752 possible dioxygenase reductase subunit. | PFAM: Rieske [2Fe-2S] domain protein; KEGG: sme:SMa0751 putative aromatic-ring hydroxylating dioxygenase, alpha-subunit. | 0.976 |
Pden_1188 | Pden_1197 | Pden_1188 | Pden_1197 | PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sme:SMa0752 possible dioxygenase reductase subunit. | PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ppu:PP_4753 N-methylproline demethylase, putative. | 0.894 |
Pden_1188 | hpbD | Pden_1188 | Pden_1187 | PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sme:SMa0752 possible dioxygenase reductase subunit. | Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein; Catalyzes the 2-epimerization of trans-4-hydroxy-L-proline betaine (tHyp-B) to cis-4-hydroxy-D-proline betaine (cHyp-B). Is involved in a catabolic pathway that degrades tHyp-B to alpha- ketoglutarate. This pathway would permit the utilization of tHyp-B as a carbon and nitrogen source in the absence of osmotic stress, since tHyp-B functions as an osmolyte and is not catabolized when it is needed as osmoprotectant. Can also catalyze the racemization of L- proline betaine. | 0.721 |
Pden_1189 | Pden_1186 | Pden_1189 | Pden_1186 | PFAM: Rieske [2Fe-2S] domain protein; KEGG: sme:SMa0751 putative aromatic-ring hydroxylating dioxygenase, alpha-subunit. | Glutathione-independent formaldehyde dehydrogenase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: atc:AGR_C_2885 hypothetical protein. | 0.651 |