node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pden_0512 | Pden_0514 | Pden_0512 | Pden_0514 | TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: rsp:RSP_2686 putative sarcosine oxidase beta subunit. | PFAM: Sarcosine oxidase, delta subunit, heterotetrameric; KEGG: rsp:RSP_2688 putative sarcosine oxidase delta subunit protein. | 0.991 |
Pden_0512 | Pden_0515 | Pden_0512 | Pden_0515 | TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: rsp:RSP_2686 putative sarcosine oxidase beta subunit. | TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; KEGG: rsp:RSP_2689 putative sarcosine oxidase, alpha subunit; Belongs to the GcvT family. | 0.998 |
Pden_0512 | Pden_0516 | Pden_0512 | Pden_0516 | TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: rsp:RSP_2686 putative sarcosine oxidase beta subunit. | PFAM: Sarcosine oxidase, gamma subunit; KEGG: rsp:RSP_2690 putative sarcosine oxidase gamma subunit. | 0.977 |
Pden_0512 | Pden_0729 | Pden_0512 | Pden_0729 | TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: rsp:RSP_2686 putative sarcosine oxidase beta subunit. | PFAM: aminotransferase, class V; KEGG: rsp:RSP_0245 serine-pyruvate aminotransferase/aspartate aminotransferase. | 0.922 |
Pden_0512 | Pden_3664 | Pden_0512 | Pden_3664 | TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: rsp:RSP_2686 putative sarcosine oxidase beta subunit. | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.903 |
Pden_0512 | bhcA | Pden_0512 | Pden_3921 | TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: rsp:RSP_2686 putative sarcosine oxidase beta subunit. | Serine-glyoxylate aminotransferase apoenzyme; Catalyzes the transamination of glyoxylate into glycine using L-aspartate as the preferred amino group donor. Is essential for the growth of P.denitrificans in the presence of glycolate and glyoxylate since it functions in glyoxylate assimilation via the beta- hydroxyaspartate cycle (BHAC). Can catalyze the reverse reaction in vitro, and also use L-serine and L-glutamate as amino group donor, but with much less efficiency than L-aspartate. | 0.922 |
Pden_0512 | gcvP | Pden_0512 | Pden_2346 | TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: rsp:RSP_2686 putative sarcosine oxidase beta subunit. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.917 |
Pden_0512 | glyA | Pden_0512 | Pden_0920 | TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: rsp:RSP_2686 putative sarcosine oxidase beta subunit. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
Pden_0512 | hemA | Pden_0512 | Pden_1822 | TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: rsp:RSP_2686 putative sarcosine oxidase beta subunit. | KEGG: rde:RD1_2827 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.906 |
Pden_0514 | Pden_0512 | Pden_0514 | Pden_0512 | PFAM: Sarcosine oxidase, delta subunit, heterotetrameric; KEGG: rsp:RSP_2688 putative sarcosine oxidase delta subunit protein. | TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: rsp:RSP_2686 putative sarcosine oxidase beta subunit. | 0.991 |
Pden_0514 | Pden_0515 | Pden_0514 | Pden_0515 | PFAM: Sarcosine oxidase, delta subunit, heterotetrameric; KEGG: rsp:RSP_2688 putative sarcosine oxidase delta subunit protein. | TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; KEGG: rsp:RSP_2689 putative sarcosine oxidase, alpha subunit; Belongs to the GcvT family. | 0.999 |
Pden_0514 | Pden_0516 | Pden_0514 | Pden_0516 | PFAM: Sarcosine oxidase, delta subunit, heterotetrameric; KEGG: rsp:RSP_2688 putative sarcosine oxidase delta subunit protein. | PFAM: Sarcosine oxidase, gamma subunit; KEGG: rsp:RSP_2690 putative sarcosine oxidase gamma subunit. | 0.999 |
Pden_0514 | Pden_0729 | Pden_0514 | Pden_0729 | PFAM: Sarcosine oxidase, delta subunit, heterotetrameric; KEGG: rsp:RSP_2688 putative sarcosine oxidase delta subunit protein. | PFAM: aminotransferase, class V; KEGG: rsp:RSP_0245 serine-pyruvate aminotransferase/aspartate aminotransferase. | 0.900 |
Pden_0514 | Pden_3664 | Pden_0514 | Pden_3664 | PFAM: Sarcosine oxidase, delta subunit, heterotetrameric; KEGG: rsp:RSP_2688 putative sarcosine oxidase delta subunit protein. | L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.904 |
Pden_0514 | bhcA | Pden_0514 | Pden_3921 | PFAM: Sarcosine oxidase, delta subunit, heterotetrameric; KEGG: rsp:RSP_2688 putative sarcosine oxidase delta subunit protein. | Serine-glyoxylate aminotransferase apoenzyme; Catalyzes the transamination of glyoxylate into glycine using L-aspartate as the preferred amino group donor. Is essential for the growth of P.denitrificans in the presence of glycolate and glyoxylate since it functions in glyoxylate assimilation via the beta- hydroxyaspartate cycle (BHAC). Can catalyze the reverse reaction in vitro, and also use L-serine and L-glutamate as amino group donor, but with much less efficiency than L-aspartate. | 0.900 |
Pden_0514 | gcvP | Pden_0514 | Pden_2346 | PFAM: Sarcosine oxidase, delta subunit, heterotetrameric; KEGG: rsp:RSP_2688 putative sarcosine oxidase delta subunit protein. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.905 |
Pden_0514 | glyA | Pden_0514 | Pden_0920 | PFAM: Sarcosine oxidase, delta subunit, heterotetrameric; KEGG: rsp:RSP_2688 putative sarcosine oxidase delta subunit protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.912 |
Pden_0514 | hemA | Pden_0514 | Pden_1822 | PFAM: Sarcosine oxidase, delta subunit, heterotetrameric; KEGG: rsp:RSP_2688 putative sarcosine oxidase delta subunit protein. | KEGG: rde:RD1_2827 5-aminolevulinic acid synthase; TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aminotransferase, class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.900 |
Pden_0515 | Pden_0512 | Pden_0515 | Pden_0512 | TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; KEGG: rsp:RSP_2689 putative sarcosine oxidase, alpha subunit; Belongs to the GcvT family. | TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: rsp:RSP_2686 putative sarcosine oxidase beta subunit. | 0.998 |
Pden_0515 | Pden_0514 | Pden_0515 | Pden_0514 | TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: FAD dependent oxidoreductase; glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel; KEGG: rsp:RSP_2689 putative sarcosine oxidase, alpha subunit; Belongs to the GcvT family. | PFAM: Sarcosine oxidase, delta subunit, heterotetrameric; KEGG: rsp:RSP_2688 putative sarcosine oxidase delta subunit protein. | 0.999 |