STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccoPCytochrome c oxidase, cbb3-type, subunit iii; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex. CcoP subunit is required for transferring electrons from donor cytochrome c via its heme groups to CcoO subunit. From there, electrons are shuttled to the catalytic binuclear center of CcoN subunit where oxygen reduction takes place. The complex also functions as a proton pump (349 aa)    
Predicted Functional Partners:
Pden_1848
Cytochrome c oxidase, cbb3-type, subunit i; Belongs to the heme-copper respiratory oxidase family
 
 0.999
Pden_1847
TIGRFAM: cytochrome c oxidase, cbb3-type, subunit II; PFAM: cytochrome C oxidase, mono-heme subunit/FixO; KEGG: rde:RD1_1271 cytochrome c oxidase, cbb3-type, subunit II
 
 
 0.998
Pden_1846
Cytochrome c oxidase cbb3-type subunit iv; PFAM: Cbb3-type cytochrome oxidase component; KEGG: sit:TM1040_2543 Cbb3-type cytochrome oxidase component
 
 0.990
Pden_1843
PFAM: FixH family protein; KEGG: rsp:RSP_0691 RdxH
 
 
 
 0.949
Pden_1844
TIGRFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: rsp:RSP_0692 iron-sulfur cluster-binding protein
 
  
 0.934
Pden_4321
Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
   
 0.880
Pden_1842
Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: rsp:RSP_0690 copper-translocating P-type ATPase, RdxI
 
   
 0.877
Pden_4317
PFAM: cytochrome c oxidase, subunit III; KEGG: rsp:RSP_1829 cytochrome c oxidase, aa3-type, subunit III
  
 0.869
Pden_1938
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
  
 0.868
Pden_3028
Cytochrome c oxidase subunit i; Belongs to the heme-copper respiratory oxidase family
  
 0.868
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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