STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pden_2560PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mlo:mlr6976 enoyl-CoA hydratase. (268 aa)    
Predicted Functional Partners:
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
 0.820
Pden_1935
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
 0.811
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
   
 
 0.807
Pden_1355
PFAM: Methionine synthase, vitamin-B12 independent; KEGG: atc:AGR_L_2018 tetrahydropteroyltriglutamate methyltransferase.
     
 0.806
Pden_3952
PFAM: homocysteine S-methyltransferase; KEGG: rsp:RSP_2124 methionine synthase I.
     
 0.806
Pden_1933
KEGG: sit:TM1040_0585 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes.
   
 
  0.803
Pden_0631
3-mercaptopyruvate sulfurtransferase; PFAM: Rhodanese domain protein; KEGG: rsp:RSP_0885 thiosulfate sulfurtransferase, rhodanese-like.
  
 
  0.801
Pden_0648
PFAM: aminotransferase, class I and II; KEGG: rsp:RSP_0871 putative aminotransferase.
     
  0.800
Pden_2557
KEGG: sil:SPO1135 hypothetical protein.
       0.782
Pden_2558
PFAM: SirA family protein; KEGG: sil:SPO1895 SirA family protein; Belongs to the sulfur carrier protein TusA family.
       0.782
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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