node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pden_0524 | Pden_1418 | Pden_0524 | Pden_1418 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: rsp:RSP_2912 predicted pyrophosphatase. | 0.461 |
Pden_0524 | Pden_4001 | Pden_0524 | Pden_4001 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Purine nucleosidase; PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: rsp:RSP_2914 nucleoside hydrolase. | 0.961 |
Pden_0524 | deoA | Pden_0524 | Pden_2222 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.969 |
Pden_0524 | guaA | Pden_0524 | Pden_3696 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.680 |
Pden_0524 | guaB | Pden_0524 | Pden_0592 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.528 |
Pden_0524 | nadD | Pden_0524 | Pden_1318 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.408 |
Pden_0524 | surE | Pden_0524 | Pden_2731 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.942 |
Pden_1418 | Pden_0524 | Pden_1418 | Pden_0524 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: rsp:RSP_2912 predicted pyrophosphatase. | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.461 |
Pden_1418 | Pden_4001 | Pden_1418 | Pden_4001 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: rsp:RSP_2912 predicted pyrophosphatase. | Purine nucleosidase; PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: rsp:RSP_2914 nucleoside hydrolase. | 0.541 |
Pden_1418 | guaA | Pden_1418 | Pden_3696 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: rsp:RSP_2912 predicted pyrophosphatase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.903 |
Pden_1418 | nadD | Pden_1418 | Pden_1318 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: rsp:RSP_2912 predicted pyrophosphatase. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.930 |
Pden_1418 | pyrH | Pden_1418 | Pden_3993 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: rsp:RSP_2912 predicted pyrophosphatase. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.900 |
Pden_1418 | surE | Pden_1418 | Pden_2731 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: rsp:RSP_2912 predicted pyrophosphatase. | 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.942 |
Pden_4001 | Pden_0524 | Pden_4001 | Pden_0524 | Purine nucleosidase; PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: rsp:RSP_2914 nucleoside hydrolase. | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.961 |
Pden_4001 | Pden_1418 | Pden_4001 | Pden_1418 | Purine nucleosidase; PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: rsp:RSP_2914 nucleoside hydrolase. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: rsp:RSP_2912 predicted pyrophosphatase. | 0.541 |
Pden_4001 | surE | Pden_4001 | Pden_2731 | Purine nucleosidase; PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: rsp:RSP_2914 nucleoside hydrolase. | 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.940 |
deoA | Pden_0524 | Pden_2222 | Pden_0524 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.969 |
deoA | guaA | Pden_2222 | Pden_3696 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.487 |
deoA | guaB | Pden_2222 | Pden_0592 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.412 |
deoA | surE | Pden_2222 | Pden_2731 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.936 |