node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pden_0399 | cmk | Pden_0399 | Pden_3784 | Farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; KEGG: rsp:RSP_1135 geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | KEGG: rsp:RSP_3591 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | 0.401 |
Pden_0399 | dxr | Pden_0399 | Pden_3997 | Farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; KEGG: rsp:RSP_1135 geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.585 |
Pden_0399 | dxs | Pden_0399 | Pden_0400 | Farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; KEGG: rsp:RSP_1135 geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.943 |
Pden_0399 | ispDF | Pden_0399 | Pden_3667 | Farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; KEGG: rsp:RSP_1135 geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 0.527 |
Pden_0399 | ispE | Pden_0399 | Pden_0423 | Farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; KEGG: rsp:RSP_1135 geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.472 |
Pden_0399 | ispG | Pden_0399 | Pden_1820 | Farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; KEGG: rsp:RSP_1135 geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.539 |
Pden_0399 | ispH | Pden_0399 | Pden_3619 | Farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; KEGG: rsp:RSP_1135 geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.943 |
Pden_3616 | ispH | Pden_3616 | Pden_3619 | PFAM: protein of unknown function UPF0126; KEGG: sil:SPO3213 hypothetical protein. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.721 |
Pden_3616 | rnhA | Pden_3616 | Pden_3617 | PFAM: protein of unknown function UPF0126; KEGG: sil:SPO3213 hypothetical protein. | Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.868 |
Pden_3786 | cmk | Pden_3786 | Pden_3784 | SSU ribosomal protein S1P; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | KEGG: rsp:RSP_3591 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | 0.975 |
Pden_3786 | ispDF | Pden_3786 | Pden_3667 | SSU ribosomal protein S1P; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 0.649 |
Pden_3786 | ispE | Pden_3786 | Pden_0423 | SSU ribosomal protein S1P; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | 0.482 |
Pden_3786 | ispG | Pden_3786 | Pden_1820 | SSU ribosomal protein S1P; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. | 0.455 |
Pden_3786 | ispH | Pden_3786 | Pden_3619 | SSU ribosomal protein S1P; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.913 |
cmk | Pden_0399 | Pden_3784 | Pden_0399 | KEGG: rsp:RSP_3591 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | Farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; KEGG: rsp:RSP_1135 geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | 0.401 |
cmk | Pden_3786 | Pden_3784 | Pden_3786 | KEGG: rsp:RSP_3591 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | SSU ribosomal protein S1P; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.975 |
cmk | ispDF | Pden_3784 | Pden_3667 | KEGG: rsp:RSP_3591 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF); In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily. | 0.525 |
cmk | ispH | Pden_3784 | Pden_3619 | KEGG: rsp:RSP_3591 cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.862 |
dxr | Pden_0399 | Pden_3997 | Pden_0399 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; KEGG: rsp:RSP_1135 geranylgeranyl pyrophosphate synthetase; Belongs to the FPP/GGPP synthase family. | 0.585 |
dxr | dxs | Pden_3997 | Pden_0400 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.994 |