node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pden_2608 | Pden_3908 | Pden_2608 | Pden_3908 | KpsF/GutQ family protein; KEGG: rsp:RSP_1153 sugar phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | PFAM: protein of unknown function DUF1009; KEGG: rsp:RSP_2715 hypothetical protein. | 0.789 |
Pden_2608 | Pden_3909 | Pden_2608 | Pden_3909 | KpsF/GutQ family protein; KEGG: rsp:RSP_1153 sugar phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.901 |
Pden_2608 | bamA | Pden_2608 | Pden_3999 | KpsF/GutQ family protein; KEGG: rsp:RSP_1153 sugar phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | Surface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.657 |
Pden_2608 | kdsA | Pden_2608 | Pden_1233 | KpsF/GutQ family protein; KEGG: rsp:RSP_1153 sugar phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: sil:SPO0947 2-dehydro-3-deoxyphosphooctonate aldolase. | 0.992 |
Pden_2608 | lpxA | Pden_2608 | Pden_3907 | KpsF/GutQ family protein; KEGG: rsp:RSP_1153 sugar phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.899 |
Pden_2608 | lpxC | Pden_2608 | Pden_4486 | KpsF/GutQ family protein; KEGG: rsp:RSP_1153 sugar phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.896 |
Pden_2608 | lpxD | Pden_2608 | Pden_1241 | KpsF/GutQ family protein; KEGG: rsp:RSP_1153 sugar phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.900 |
Pden_2608 | lpxK | Pden_2608 | Pden_2094 | KpsF/GutQ family protein; KEGG: rsp:RSP_1153 sugar phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.905 |
Pden_3908 | Pden_2608 | Pden_3908 | Pden_2608 | PFAM: protein of unknown function DUF1009; KEGG: rsp:RSP_2715 hypothetical protein. | KpsF/GutQ family protein; KEGG: rsp:RSP_1153 sugar phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | 0.789 |
Pden_3908 | Pden_3909 | Pden_3908 | Pden_3909 | PFAM: protein of unknown function DUF1009; KEGG: rsp:RSP_2715 hypothetical protein. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.954 |
Pden_3908 | bamA | Pden_3908 | Pden_3999 | PFAM: protein of unknown function DUF1009; KEGG: rsp:RSP_2715 hypothetical protein. | Surface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.688 |
Pden_3908 | fabZ | Pden_3908 | Pden_3906 | PFAM: protein of unknown function DUF1009; KEGG: rsp:RSP_2715 hypothetical protein. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.882 |
Pden_3908 | kdsA | Pden_3908 | Pden_1233 | PFAM: protein of unknown function DUF1009; KEGG: rsp:RSP_2715 hypothetical protein. | TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: sil:SPO0947 2-dehydro-3-deoxyphosphooctonate aldolase. | 0.640 |
Pden_3908 | lpxA | Pden_3908 | Pden_3907 | PFAM: protein of unknown function DUF1009; KEGG: rsp:RSP_2715 hypothetical protein. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.967 |
Pden_3908 | lpxC | Pden_3908 | Pden_4486 | PFAM: protein of unknown function DUF1009; KEGG: rsp:RSP_2715 hypothetical protein. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.761 |
Pden_3908 | lpxD | Pden_3908 | Pden_1241 | PFAM: protein of unknown function DUF1009; KEGG: rsp:RSP_2715 hypothetical protein. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.802 |
Pden_3908 | lpxK | Pden_3908 | Pden_2094 | PFAM: protein of unknown function DUF1009; KEGG: rsp:RSP_2715 hypothetical protein. | lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.804 |
Pden_3909 | Pden_2608 | Pden_3909 | Pden_2608 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | KpsF/GutQ family protein; KEGG: rsp:RSP_1153 sugar phosphate isomerase; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily. | 0.901 |
Pden_3909 | Pden_3908 | Pden_3909 | Pden_3908 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | PFAM: protein of unknown function DUF1009; KEGG: rsp:RSP_2715 hypothetical protein. | 0.954 |
Pden_3909 | bamA | Pden_3909 | Pden_3999 | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Surface antigen (D15); Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | 0.740 |