node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Pden_2575 | clpX | Pden_2575 | Pden_1266 | PFAM: Polynucleotide adenylyltransferase region; KEGG: rsp:RSP_1205 poly A polymerase family protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.448 |
Pden_2575 | hfq | Pden_2575 | Pden_4124 | PFAM: Polynucleotide adenylyltransferase region; KEGG: rsp:RSP_1205 poly A polymerase family protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.765 |
Pden_2575 | pnp | Pden_2575 | Pden_2759 | PFAM: Polynucleotide adenylyltransferase region; KEGG: rsp:RSP_1205 poly A polymerase family protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 3' exoribonuclease; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.826 |
Pden_2575 | rne | Pden_2575 | Pden_2965 | PFAM: Polynucleotide adenylyltransferase region; KEGG: rsp:RSP_1205 poly A polymerase family protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | RNAse E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. | 0.484 |
Pden_4125 | Pden_4126 | Pden_4125 | Pden_4126 | PFAM: cation transporter; KEGG: rsp:RSP_2842 potassium uptake transporter, transmembrane subunit, TrkH. | PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: rsp:RSP_2841 potassium uptake tranporter, NAD-binding subunit, TrkA. | 0.993 |
Pden_4125 | hflX | Pden_4125 | Pden_4123 | PFAM: cation transporter; KEGG: rsp:RSP_2842 potassium uptake transporter, transmembrane subunit, TrkH. | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.741 |
Pden_4125 | hfq | Pden_4125 | Pden_4124 | PFAM: cation transporter; KEGG: rsp:RSP_2842 potassium uptake transporter, transmembrane subunit, TrkH. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.741 |
Pden_4126 | Pden_4125 | Pden_4126 | Pden_4125 | PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: rsp:RSP_2841 potassium uptake tranporter, NAD-binding subunit, TrkA. | PFAM: cation transporter; KEGG: rsp:RSP_2842 potassium uptake transporter, transmembrane subunit, TrkH. | 0.993 |
Pden_4126 | hflX | Pden_4126 | Pden_4123 | PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: rsp:RSP_2841 potassium uptake tranporter, NAD-binding subunit, TrkA. | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.838 |
Pden_4126 | hfq | Pden_4126 | Pden_4124 | PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: rsp:RSP_2841 potassium uptake tranporter, NAD-binding subunit, TrkA. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.774 |
clpX | Pden_2575 | Pden_1266 | Pden_2575 | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | PFAM: Polynucleotide adenylyltransferase region; KEGG: rsp:RSP_1205 poly A polymerase family protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.448 |
clpX | hfq | Pden_1266 | Pden_4124 | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.770 |
glmS | glmU | Pden_0619 | Pden_0618 | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.995 |
glmS | hflX | Pden_0619 | Pden_4123 | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.412 |
glmS | hfq | Pden_0619 | Pden_4124 | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.723 |
glmU | glmS | Pden_0618 | Pden_0619 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.995 |
glmU | hfq | Pden_0618 | Pden_4124 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.800 |
hflX | Pden_4125 | Pden_4123 | Pden_4125 | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | PFAM: cation transporter; KEGG: rsp:RSP_2842 potassium uptake transporter, transmembrane subunit, TrkH. | 0.741 |
hflX | Pden_4126 | Pden_4123 | Pden_4126 | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | PFAM: TrkA-N domain protein; TrkA-C domain protein; KEGG: rsp:RSP_2841 potassium uptake tranporter, NAD-binding subunit, TrkA. | 0.838 |
hflX | glmS | Pden_4123 | Pden_0619 | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.412 |