STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hpa/tpaAminotransferase; Converts hypotaurine to alanine and sulfinoacetaldehyde, which desulfinates spontaneously to acetaldehyde and sulfite. Can also catalyze the degradation of taurine into alanine and sulfoacetaldehyde, which is stable. Has 2-fold higher aminotransferase activity with hypotaurine as the substrate. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (459 aa)    
Predicted Functional Partners:
Pden_1010
Sulfoacetaldehyde acetyltransferase; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: rsp:RSP_4011 hypothetical protein.
  
  
 0.944
Pden_1642
Sulfoacetaldehyde acetyltransferase; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: rsp:RSP_4011 hypothetical protein.
  
  
 0.944
Pden_1644
PFAM: protein of unknown function DUF1486; KEGG: rsp:RSP_4013 hypothetical protein.
  
  
  0.912
Pden_0660
Gamma-glutamyltransferase 1, Threonine peptidase, MEROPS family T03; KEGG: rru:Rru_A0385 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase.
    
 0.904
Pden_4274
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: rde:RD1_0978 transcriptional regulator, GntR family, putative.
 
   
 0.826
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
  
  
 0.611
Pden_1648
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR, HTH; aminotransferase, class I and II; KEGG: rsp:RSP_4017 transcriptional regulator, GntR family.
 
   
 0.578
Pden_0180
PFAM: aldehyde dehydrogenase; KEGG: mlo:mll7197 dehydrogenase.
     
 0.529
Pden_1254
PFAM: aldehyde dehydrogenase; KEGG: bxe:Bxe_A3401 betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
    
 0.529
Pden_1991
PFAM: aldehyde dehydrogenase; KEGG: rme:Rmet_0158 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
     
 0.529
Your Current Organism:
Paracoccus denitrificans
NCBI taxonomy Id: 318586
Other names: P. denitrificans PD1222, Paracoccus denitrificans PD1222
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