STRINGSTRING
fumC protein (Shewanella putrefaciens) - STRING interaction network
"fumC" - Fumarate hydratase class II in Shewanella putrefaciens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumCFumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily (467 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate (311 aa)
 
  0.987
ABP75994.1
PFAM- succinate dehydrogenase, cytochrome b subunit; KEGG- shm-Shewmr7_1706 succinate dehydrogenase, cytochrome b subunit (131 aa)
     
 
  0.982
ABP77151.1
PFAM- fumarate reductase respiratory complex, transmembrane subunit; KEGG- shm-Shewmr7_3623 fumarate reductase respiratory complex, transmembrane subunit (241 aa)
     
 
  0.971
ABP74086.1
KEGG- vfi-VF2334 fumarate reductase flavoprotein subunit; TIGRFAM- fumarate reductase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM- fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase (591 aa)
 
  0.963
ABP75995.1
KEGG- son-SO1926 citrate synthase; TIGRFAM- citrate synthase I; PFAM- Citrate synthase; Belongs to the citrate synthase family (428 aa)
     
  0.960
maeA
PFAM- malic enzyme domain protein; malic enzyme, NAD-binding; KEGG- son-SO3855 malate oxidoreductase; Belongs to the malic enzymes family (562 aa)
  0.960
ABP77148.1
KEGG- shm-Shewmr7_3620 succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM- succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM- 4Fe-4S ferredoxin, iron-sulfur binding domain protein (243 aa)
   
  0.958
ABP75991.1
TIGRFAM- succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG- she-Shewmr4_1634 succinate dehydrogenase and fumarate reductase iron-sulfur protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family (235 aa)
   
  0.958
ABP74085.1
KEGG- vpa-VP2841 fumarate reductase, iron-sulfur protein; TIGRFAM- succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM- ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family (246 aa)
   
  0.958
ABP75992.1
KEGG- son-SO1928 succinate dehydrogenase flavoprotein subunit; TIGRFAM- succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM- fumarate reductase/succinate dehydrogenase flavoprotein domain protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily (588 aa)
   
  0.958
Your Current Organism:
Shewanella putrefaciens
NCBI taxonomy Id: 319224
Other names: S. putrefaciens CN-32, Shewanella putrefaciens, Shewanella putrefaciens CN-32, Shewanella putrefaciens str. CN-32, Shewanella putrefaciens strain CN-32
Server load: low (14%) [HD]