STRINGSTRING
ABP74488.1 protein (Shewanella putrefaciens) - STRING interaction network
"ABP74488.1" - Replicative DNA helicase in Shewanella putrefaciens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABP74488.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins (468 aa)    
Predicted Functional Partners:
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication; Belongs to the DnaG primase family (574 aa)
 
 
  0.930
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3’ invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA’s homology-searching function (454 aa)
 
   
  0.898
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box)- 5’-TTATC[CA]A[CA]A-3’. DnaA binds to ATP and to acidic phospholipids (461 aa)
 
 
  0.898
ABP75091.1
KEGG- shm-Shewmr7_2693 DNA polymerase III, alpha subunit; TIGRFAM- DNA polymerase III, alpha subunit; PFAM- PHP C-terminal domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; SMART- phosphoesterase PHP domain protein (1157 aa)
 
   
  0.799
ABP76023.1
KEGG- son-SO2013 DNA polymerase III, gamma and tau subunits; TIGRFAM- DNA polymerase III, subunits gamma and tau; PFAM- AAA ATPase, central domain protein; SMART- AAA ATPase (957 aa)
   
 
  0.794
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (922 aa)
 
   
  0.782
priB
Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS) (101 aa)
     
 
  0.765
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (329 aa)
   
   
  0.719
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids; Belongs to the alanine racemase family (358 aa)
 
   
  0.717
pheT
KEGG- she-Shewmr4_1809 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM- phenylalanyl-tRNA synthetase, beta subunit (795 aa)
 
 
  0.714
Your Current Organism:
Shewanella putrefaciens
NCBI taxonomy Id: 319224
Other names: S. putrefaciens CN-32, Shewanella putrefaciens, Shewanella putrefaciens CN-32, Shewanella putrefaciens str. CN-32, Shewanella putrefaciens strain CN-32
Server load: low (11%) [HD]