node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABP74347.1 | ABP74348.1 | Sputcn32_0616 | Sputcn32_0617 | KEGG: son:SO4056 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | KEGG: son:SO4055 aspartokinase II/homoserine dehydrogenase, methionine-sensitive; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.986 |
ABP74347.1 | ABP74661.1 | Sputcn32_0616 | Sputcn32_0932 | KEGG: son:SO4056 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | KEGG: shm:Shewmr7_0966 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | 0.933 |
ABP74347.1 | ABP75461.1 | Sputcn32_0616 | Sputcn32_1736 | KEGG: son:SO4056 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: shm:Shewmr7_2281 cystathionine beta-lyase. | 0.932 |
ABP74347.1 | ABP76091.1 | Sputcn32_0616 | Sputcn32_2370 | KEGG: son:SO4056 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | TIGRFAM: cysteine synthases; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: son:SO2903 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.983 |
ABP74347.1 | ABP76454.1 | Sputcn32_0616 | Sputcn32_2735 | KEGG: son:SO4056 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | KEGG: shm:Shewmr7_1209 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.940 |
ABP74347.1 | ABP76481.1 | Sputcn32_0616 | Sputcn32_2762 | KEGG: son:SO4056 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | PFAM: Methionine synthase, vitamin-B12 independent; Cobalamin-independent synthase MetE, N-terminal domain protein; KEGG: cps:CPS_1151 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | 0.952 |
ABP74347.1 | ABP76680.1 | Sputcn32_0616 | Sputcn32_2965 | KEGG: son:SO4056 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.980 |
ABP74347.1 | luxS | Sputcn32_0616 | Sputcn32_0938 | KEGG: son:SO4056 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.931 |
ABP74347.1 | metE | Sputcn32_0616 | Sputcn32_3172 | KEGG: son:SO4056 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.952 |
ABP74348.1 | ABP74347.1 | Sputcn32_0617 | Sputcn32_0616 | KEGG: son:SO4055 aspartokinase II/homoserine dehydrogenase, methionine-sensitive; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | KEGG: son:SO4056 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | 0.986 |
ABP74348.1 | ABP74661.1 | Sputcn32_0617 | Sputcn32_0932 | KEGG: son:SO4055 aspartokinase II/homoserine dehydrogenase, methionine-sensitive; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | KEGG: shm:Shewmr7_0966 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | 0.910 |
ABP74348.1 | ABP75461.1 | Sputcn32_0617 | Sputcn32_1736 | KEGG: son:SO4055 aspartokinase II/homoserine dehydrogenase, methionine-sensitive; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: shm:Shewmr7_2281 cystathionine beta-lyase. | 0.940 |
ABP74348.1 | ABP76454.1 | Sputcn32_0617 | Sputcn32_2735 | KEGG: son:SO4055 aspartokinase II/homoserine dehydrogenase, methionine-sensitive; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | KEGG: shm:Shewmr7_1209 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.995 |
ABP74348.1 | ABP76481.1 | Sputcn32_0617 | Sputcn32_2762 | KEGG: son:SO4055 aspartokinase II/homoserine dehydrogenase, methionine-sensitive; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | PFAM: Methionine synthase, vitamin-B12 independent; Cobalamin-independent synthase MetE, N-terminal domain protein; KEGG: cps:CPS_1151 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase. | 0.940 |
ABP74348.1 | ABP76680.1 | Sputcn32_0617 | Sputcn32_2965 | KEGG: son:SO4055 aspartokinase II/homoserine dehydrogenase, methionine-sensitive; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.981 |
ABP74348.1 | luxS | Sputcn32_0617 | Sputcn32_0938 | KEGG: son:SO4055 aspartokinase II/homoserine dehydrogenase, methionine-sensitive; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.837 |
ABP74348.1 | metE | Sputcn32_0617 | Sputcn32_3172 | KEGG: son:SO4055 aspartokinase II/homoserine dehydrogenase, methionine-sensitive; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.940 |
ABP74661.1 | ABP74347.1 | Sputcn32_0932 | Sputcn32_0616 | KEGG: shm:Shewmr7_0966 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | KEGG: son:SO4056 cystathionine gamma-synthase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | 0.933 |
ABP74661.1 | ABP74348.1 | Sputcn32_0932 | Sputcn32_0617 | KEGG: shm:Shewmr7_0966 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | KEGG: son:SO4055 aspartokinase II/homoserine dehydrogenase, methionine-sensitive; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; homoserine dehydrogenase, NAD-binding; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.910 |
ABP74661.1 | ABP75461.1 | Sputcn32_0932 | Sputcn32_1736 | KEGG: shm:Shewmr7_0966 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes. | TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; KEGG: shm:Shewmr7_2281 cystathionine beta-lyase. | 0.938 |