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purT protein (Shewanella putrefaciens) - STRING interaction network
"purT" - Formate-dependent phosphoribosylglycinamide formyltransferase in Shewanella putrefaciens
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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purTFormate-dependent phosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family (391 aa)    
Predicted Functional Partners:
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1293 aa)
   
  0.992
purH
Bifunctional purine biosynthesis protein PurH; KEGG- son-SO0442 phosphoribosylaminoimidazolecarboxamide formyltransferase (543 aa)
   
  0.979
purC
PFAM- SAICAR synthetase; KEGG- shm-Shewmr7_0504 phosphoribosylaminoimidazolesuccinocarboxamide synthase (367 aa)
   
 
  0.976
purM
KEGG- shm-Shewmr7_2452 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM- phosphoribosylformylglycinamidine cyclo-ligase; PFAM- AIR synthase related protein; AIR synthase related protein domain protein (345 aa)
   
  0.972
purD
KEGG- son-SO0441 phosphoribosylamine--glycine ligase; TIGRFAM- phosphoribosylamine--glycine ligase; PFAM- phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Belongs to the GARS family (432 aa)
 
  0.964
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate (214 aa)
   
 
  0.956
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) (316 aa)
 
   
  0.941
ABP76928.1
PFAM- 5-formyltetrahydrofolate cyclo-ligase; KEGG- she-Shewmr4_3336 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family (219 aa)
   
 
  0.924
ABP76680.1
TIGRFAM- methionine synthase; PFAM- dihydropteroate synthase, DHPS; homocysteine S-methyltransferase; Methionine synthase, B12-binding module, cap domain protein; Vitamin B12 dependent methionine synthase, activation region; cobalamin B12-binding domain protein; KEGG- son-SO1030 5-methyltetrahydrofolate--homocysteine methyltransferase (1244 aa)
         
  0.917
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (417 aa)
   
 
  0.913
Your Current Organism:
Shewanella putrefaciens
NCBI taxonomy Id: 319224
Other names: S. putrefaciens CN-32, Shewanella putrefaciens, Shewanella putrefaciens CN-32, Shewanella putrefaciens str. CN-32, Shewanella putrefaciens strain CN-32
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