node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABP74275.1 | ABP76032.1 | Sputcn32_0543 | Sputcn32_2311 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: she:Shewmr4_2264 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.901 |
ABP74275.1 | ABP77328.1 | Sputcn32_0543 | Sputcn32_3620 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shm:Shewmr7_0341 HAD-superfamily hydrolase, subfamily IA, variant 1. | 0.900 |
ABP74275.1 | cdd | Sputcn32_0543 | Sputcn32_1568 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.980 |
ABP74275.1 | deoA | Sputcn32_0543 | Sputcn32_2821 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.981 |
ABP74275.1 | deoD | Sputcn32_0543 | Sputcn32_1657 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | TIGRFAM: purine nucleoside phosphorylase; PFAM: purine and other phosphorylases, family 1; KEGG: son:SO2719 purine nucleoside phosphorylase. | 0.932 |
ABP74275.1 | deoD-2 | Sputcn32_0543 | Sputcn32_2819 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | TIGRFAM: purine nucleoside phosphorylase; PFAM: purine and other phosphorylases, family 1; KEGG: son:SO1221 purine nucleoside phosphorylase. | 0.929 |
ABP74275.1 | tdk | Sputcn32_0543 | Sputcn32_2506 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | PFAM: thymidine kinase; KEGG: son:SO3140 thymidine kinase. | 0.917 |
ABP76032.1 | ABP74275.1 | Sputcn32_2311 | Sputcn32_0543 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: she:Shewmr4_2264 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | 0.901 |
ABP76032.1 | ABP77328.1 | Sputcn32_2311 | Sputcn32_3620 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: she:Shewmr4_2264 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shm:Shewmr7_0341 HAD-superfamily hydrolase, subfamily IA, variant 1. | 0.923 |
ABP76032.1 | cdd | Sputcn32_2311 | Sputcn32_1568 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: she:Shewmr4_2264 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.921 |
ABP76032.1 | deoA | Sputcn32_2311 | Sputcn32_2821 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: she:Shewmr4_2264 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.923 |
ABP76032.1 | deoD | Sputcn32_2311 | Sputcn32_1657 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: she:Shewmr4_2264 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | TIGRFAM: purine nucleoside phosphorylase; PFAM: purine and other phosphorylases, family 1; KEGG: son:SO2719 purine nucleoside phosphorylase. | 0.918 |
ABP76032.1 | deoD-2 | Sputcn32_2311 | Sputcn32_2819 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: she:Shewmr4_2264 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | TIGRFAM: purine nucleoside phosphorylase; PFAM: purine and other phosphorylases, family 1; KEGG: son:SO1221 purine nucleoside phosphorylase. | 0.918 |
ABP76032.1 | dut | Sputcn32_2311 | Sputcn32_0460 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: she:Shewmr4_2264 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |
ABP76032.1 | tdk | Sputcn32_2311 | Sputcn32_2506 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: she:Shewmr4_2264 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | PFAM: thymidine kinase; KEGG: son:SO3140 thymidine kinase. | 0.923 |
ABP76032.1 | thyA | Sputcn32_2311 | Sputcn32_1146 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: she:Shewmr4_2264 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.903 |
ABP76032.1 | tmk | Sputcn32_2311 | Sputcn32_2214 | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: she:Shewmr4_2264 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.910 |
ABP77328.1 | ABP74275.1 | Sputcn32_3620 | Sputcn32_0543 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shm:Shewmr7_0341 HAD-superfamily hydrolase, subfamily IA, variant 1. | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. | 0.900 |
ABP77328.1 | ABP76032.1 | Sputcn32_3620 | Sputcn32_2311 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shm:Shewmr7_0341 HAD-superfamily hydrolase, subfamily IA, variant 1. | 5'-nucleotidase; PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: she:Shewmr4_2264 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.923 |
ABP77328.1 | cdd | Sputcn32_3620 | Sputcn32_1568 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shm:Shewmr7_0341 HAD-superfamily hydrolase, subfamily IA, variant 1. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. | 0.900 |