node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABP74021.1 | coaD | Sputcn32_0288 | Sputcn32_3888 | Putative methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.871 |
ABP74187.1 | coaD | Sputcn32_0455 | Sputcn32_3888 | PFAM: YicC N-terminal domain protein; domain of unknown function DUF1732; KEGG: shm:Shewmr7_0351 hypothetical protein. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.725 |
ABP74193.1 | ABP74786.1 | Sputcn32_0461 | Sputcn32_1058 | Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | FMN adenylyltransferase / riboflavin kinase; KEGG: she:Shewmr4_2958 riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | 0.632 |
ABP74193.1 | ABP76208.1 | Sputcn32_0461 | Sputcn32_2487 | Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | PFAM: protein of unknown function DUF479; KEGG: shm:Shewmr7_1444 protein of unknown function DUF479. | 0.900 |
ABP74193.1 | coaA | Sputcn32_0461 | Sputcn32_3774 | Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: she:Shewmr4_0183 pantothenate kinase. | 0.923 |
ABP74193.1 | coaD | Sputcn32_0461 | Sputcn32_3888 | Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.953 |
ABP74193.1 | coaE | Sputcn32_0461 | Sputcn32_3426 | Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.684 |
ABP74193.1 | metK | Sputcn32_0461 | Sputcn32_0871 | Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.402 |
ABP74786.1 | ABP74193.1 | Sputcn32_1058 | Sputcn32_0461 | FMN adenylyltransferase / riboflavin kinase; KEGG: she:Shewmr4_2958 riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.632 |
ABP74786.1 | coaD | Sputcn32_1058 | Sputcn32_3888 | FMN adenylyltransferase / riboflavin kinase; KEGG: she:Shewmr4_2958 riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.681 |
ABP74786.1 | coaE | Sputcn32_1058 | Sputcn32_3426 | FMN adenylyltransferase / riboflavin kinase; KEGG: she:Shewmr4_2958 riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.539 |
ABP74786.1 | guaA | Sputcn32_1058 | Sputcn32_2645 | FMN adenylyltransferase / riboflavin kinase; KEGG: she:Shewmr4_2958 riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.492 |
ABP74786.1 | metK | Sputcn32_1058 | Sputcn32_0871 | FMN adenylyltransferase / riboflavin kinase; KEGG: she:Shewmr4_2958 riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; Belongs to the ribF family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.493 |
ABP76208.1 | ABP74193.1 | Sputcn32_2487 | Sputcn32_0461 | PFAM: protein of unknown function DUF479; KEGG: shm:Shewmr7_1444 protein of unknown function DUF479. | Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.900 |
ABP76208.1 | coaA | Sputcn32_2487 | Sputcn32_3774 | PFAM: protein of unknown function DUF479; KEGG: shm:Shewmr7_1444 protein of unknown function DUF479. | TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: she:Shewmr4_0183 pantothenate kinase. | 0.910 |
ABP76208.1 | coaD | Sputcn32_2487 | Sputcn32_3888 | PFAM: protein of unknown function DUF479; KEGG: shm:Shewmr7_1444 protein of unknown function DUF479. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.902 |
coaA | ABP74193.1 | Sputcn32_3774 | Sputcn32_0461 | TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: she:Shewmr4_0183 pantothenate kinase. | Phosphopantothenoylcysteine decarboxylase / Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.923 |
coaA | ABP76208.1 | Sputcn32_3774 | Sputcn32_2487 | TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: she:Shewmr4_0183 pantothenate kinase. | PFAM: protein of unknown function DUF479; KEGG: shm:Shewmr7_1444 protein of unknown function DUF479. | 0.910 |
coaA | coaD | Sputcn32_3774 | Sputcn32_3888 | TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: she:Shewmr4_0183 pantothenate kinase. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.929 |
coaA | coaE | Sputcn32_3774 | Sputcn32_3426 | TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: she:Shewmr4_0183 pantothenate kinase. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.432 |