STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANN21821.1ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (648 aa)    
Predicted Functional Partners:
ANN15224.1
Peptide ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ABC transporter superfamily.
     
0.861
ANN15390.1
Proline/glycine betaine ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     
0.745
ANN17110.1
ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
0.743
ANN17109.1
Transmembrane transport protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.661
ANN17111.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.635
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.546
arc
Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
 
  0.536
ANN17115.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.524
ANN17114.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.511
ANN17113.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.482
Your Current Organism:
Amycolatopsis orientalis
NCBI taxonomy Id: 31958
Other names: A. orientalis, ATCC 19795, Actinoplanes sp. ATCC 53771, Amycolatopsis orientalis orientalis, Amycolatopsis orientalis subsp. orientalis, CIP 107113, DSM 40040, IFO 12806, IMSNU 20058, ISP 5040, JCM 4235, JCM 4600, KCTC 9412, NBRC 12806, NRRL 2450, Nocardia orientalis, Streptomyces orientalis, UNIQEM 181, VKM Ac-866
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.