STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdxYPyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. (299 aa)    
Predicted Functional Partners:
pdxH
Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
    
 0.928
pdxT
Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
    
 0.916
pdxS
Pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
   
 0.915
Dgeo_1685
PFAM: aldo/keto reductase: (1.3e-42); KEGG: dra:DR1890 oxidoreductase, putative, ev=1e-138, 83% identity.
    
  0.900
Dgeo_0145
PFAM: Enoyl-CoA hydratase/isomerase: (2e-31); KEGG: dra:DR0114 enoyl-CoA hydratase, putative, ev=1e-88, 67% identity.
       0.662
atpA
V-type H+-ATPase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.
 
      0.595
Dgeo_1426
TIGRFAM: Protein of unknown function UPF0001: (1.4e-15); KEGG: dra:DR1368 hypothetical protein, ev=2e-73, 68% identity.
  
  
 0.586
Dgeo_0146
PFAM: short-chain dehydrogenase/reductase SDR: (4.4e-10); KEGG: dra:DR0113 short chain dehydrogenase, ev=1e-137, 88% identity.
   
   0.541
Dgeo_0292
Arginase; TIGRFAM: arginase: (1.4e-115); PFAM: Arginase/agmatinase/formiminoglutamase: (2.9e-105); KEGG: dra:DR0651 arginase, ev=1e-137, 81% identity; Belongs to the arginase family.
   
 
  0.465
Dgeo_0147
PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C: (8.7e-11); KEGG: dra:DR0176 D-alanyl-D-alanine carboxypeptidase, putative, ev=1e-151, 62% identity.
       0.437
Your Current Organism:
Deinococcus geothermalis
NCBI taxonomy Id: 319795
Other names: D. geothermalis DSM 11300, Deinococcus geothermalis AG-3a, Deinococcus geothermalis CIP 105573, Deinococcus geothermalis DSM 11300, Deinococcus geothermalis str. DSM 11300, Deinococcus geothermalis strain DSM 11300
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