STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (99 aa)    
Predicted Functional Partners:
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 0.999
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.999
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.999
sigA
RNA polymerase, sigma 28 subunit; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.995
Dgeo_2159
Transcriptional regulator, MerR family; PFAM: regulatory protein, MerR: (2.2e-07) transcription activator, effector binding: (4.1e-21); KEGG: nfa:nfa2920 putative transcriptional regulator, ev=4e-21, 30% identity.
   
   0.986
Dgeo_0923
KEGG: cte:CT1161 type III restriction system endonuclease, putative, ev=0.0, 82% identity.
    
  0.980
rpsB
PFAM: ribosomal protein S2: (8.9e-93); KEGG: dra:DR1513 30S ribosomal protein S2, ev=1e-131, 89% identity; Belongs to the universal ribosomal protein uS2 family.
  
 
 0.934
Dgeo_1684
PFAM: chalcone and stilbene synthases-like: (1.1e-07) Chalcone and stilbene synthases-like: (6.6e-18) FAE1/Type III polyketide synthase-like protein: (0.00014) 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal: (2.9e-09); KEGG: dra:DR2091 chalcone synthase, putative, ev=1e-152, 77% identity.
    
  0.917
rplF
Ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
   0.916
nusA
NusA antitermination factor; Participates in both transcription termination and antitermination.
 
 
 0.902
Your Current Organism:
Deinococcus geothermalis
NCBI taxonomy Id: 319795
Other names: D. geothermalis DSM 11300, Deinococcus geothermalis AG-3a, Deinococcus geothermalis CIP 105573, Deinococcus geothermalis DSM 11300, Deinococcus geothermalis str. DSM 11300, Deinococcus geothermalis strain DSM 11300
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.