STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dgeo_0405PFAM: electron transport protein SCO1/SenC: (4.6e-09); KEGG: dra:DR0597 hypothetical protein, ev=5e-68, 58% identity. (229 aa)    
Predicted Functional Partners:
Dgeo_0407
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 
 
 0.949
Dgeo_0406
PFAM: cytochrome c oxidase, subunit III: (7.3e-11) cytochrome c oxidase, subunit I: (6e-176); KEGG: dra:DR2620 cytochrome c oxidase, subunit I / III, ev=0.0, 82% identity; Belongs to the heme-copper respiratory oxidase family.
  
  
 0.934
Dgeo_1960
Thioredoxin; KEGG: dra:DR0948 hypothetical protein, ev=7e-65, 76% identity.
 
 
 0.731
Dgeo_0016
PFAM: cytochrome c oxidase, subunit II: (1.1e-19); KEGG: gka:GK1547 cytochrome c oxidase (b(o/a)3-type) chain II, ev=2e-27, 39% identity.
 
 
 0.690
ctaB
Cytochrome c oxidase assembly factor, CtaB; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
  
 0.683
Dgeo_0409
PFAM: cytochrome oxidase assembly: (2e-06); KEGG: dra:DR2617 cytochrome AA3-controlling protein CtaA, putative, ev=1e-133, 75% identity.
  
 
 0.654
Dgeo_1469
PFAM: cytochrome c, class I: (3.6e-07); KEGG: dra:DR2487 cytochrome c4, putative, ev=1e-62, 54% identity.
 
   
 0.594
Dgeo_0581
copper(I)-binding protein, DUF461; PFAM: protein of unknown function DUF461: (5.9e-30); KEGG: dra:DR1885 hypothetical protein, ev=2e-31, 48% identity.
 
   
 0.549
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
       0.486
Your Current Organism:
Deinococcus geothermalis
NCBI taxonomy Id: 319795
Other names: D. geothermalis DSM 11300, Deinococcus geothermalis AG-3a, Deinococcus geothermalis CIP 105573, Deinococcus geothermalis DSM 11300, Deinococcus geothermalis str. DSM 11300, Deinococcus geothermalis strain DSM 11300
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