STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgkPFAM: phosphoglycerate kinase: (1.8e-194); KEGG: dra:DR1342 phosphoglycerate kinase, ev=1e-172, 77% identity; Belongs to the phosphoglycerate kinase family. (389 aa)    
Predicted Functional Partners:
Dgeo_1133
KEGG: dra:DR1343 glyceraldehyde 3-phosphate dehydrogenase, ev=1e-158, 83% identity; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I: (1.8e-183); PFAM: glyceraldehyde 3-phosphate dehydrogenase: (1.3e-98); Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 0.999
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 0.999
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.991
pgi
PFAM: phosphoglucose isomerase (PGI): (7.5e-272); KEGG: dra:DR1742 glucose-6-phosphate isomerase, ev=0.0, 77% identity.
  
 
 0.928
Dgeo_2083
Fructose-1,6-bisphosphate aldolase, class II; KEGG: dra:DR1589 fructose-bisphosphate aldolase, ev=1e-152, 88% identity; TIGRFAM: ketose-bisphosphate aldolases: (5.7e-100) fructose-1,6-bisphosphate aldolase, class II: (6.8e-209); PFAM: ketose-bisphosphate aldolase, class-II: (1.9e-127).
  
 
 0.925
apgM
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
    
 0.915
Dgeo_0005
PFAM: pyruvate kinase: (9.6e-166); KEGG: dra:DR2635 pyruvate kinase, ev=0.0, 86% identity; Belongs to the pyruvate kinase family.
 
 
 0.908
Dgeo_2228
PFAM: Phosphoglycerate mutase: (1.1e-37); KEGG: dra:DR0602 phosphoglycerate mutase-related protein, ev=1e-70, 67% identity.
     
 0.907
Dgeo_2265
Metalloenzyme, phosphoglyceromutase related protein; PFAM: metalloenzyme: (7.2e-06); KEGG: dra:DR0122 hypothetical protein, ev=2e-97, 63% identity.
  
  
 0.838
Dgeo_2173
Phosphocarrier protein HPr / PTS system D-fructose-specific IIA component (F1P-forming), Frc family; TIGRFAM: Phosphoenolpyruvate-protein phosphotransferase: (4.6e-148); PFAM: phosphocarrier HPr protein: (1.8e-09) PEP-utilizing enzyme: (2e-132) phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2: (1.2e-60) PEP-utilising enzyme, mobile region: (5.7e-24) PEP-utilising enzyme-like: (1.5e-23); KEGG: dra:DRB0075 PTS system, multiphosphoryl transfer protein, domains EI, HPr, and fructose, ev=0.0, 74% identity; TC 4.A.2.1.1.
  
  
 0.767
Your Current Organism:
Deinococcus geothermalis
NCBI taxonomy Id: 319795
Other names: D. geothermalis DSM 11300, Deinococcus geothermalis AG-3a, Deinococcus geothermalis CIP 105573, Deinococcus geothermalis DSM 11300, Deinococcus geothermalis str. DSM 11300, Deinococcus geothermalis strain DSM 11300
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.