STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dgeo_1141Gamma-glutamyltransferase 2. Threonine peptidase. MEROPS family T03; PFAM: gamma-glutamyltranspeptidase: (7.6e-212); KEGG: dra:DR1524 gamma-glutamyltranspeptidase, ev=0.0, 81% identity. (531 aa)    
Predicted Functional Partners:
Dgeo_1801
TIGRFAM: conserved hypothetical protein: (1.6e-35); PFAM: Allophanate hydrolase subunit 1: (1.7e-39); KEGG: bcl:ABC3773 hypothetical protein, ev=1e-34, 40% identity.
   
 
  0.910
Dgeo_1802
PFAM: Allophanate hydrolase subunit 2: (7.6e-60); KEGG: gka:GK1501 hypothetical protein, ev=2e-49, 38% identity.
     
  0.900
Dgeo_1803
LamB/YcsF; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
     
  0.900
Dgeo_1204
KEGG: dra:DR0451 glutamine synthase, ev=0.0, 80% identity; TIGRFAM: glutamine synthetase, type I: (4.1e-212); PFAM: glutamine synthetase, catalytic region: (4.7e-146) glutamine synthetase, beta-Grasp: (3.9e-07).
     
 0.855
Dgeo_0494
PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal: (4.3e-121) Glu/Leu/Phe/Val dehydrogenase, dimerisation region: (2.9e-74); KEGG: bte:BTH_I1224 glutamate dehydrogenase, ev=0.0, 69% identity; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.818
Dgeo_0495
PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal: (2.3e-50) Glu/Leu/Phe/Val dehydrogenase, dimerisation region: (2e-55); KEGG: tth:TTC1212 glutamate dehydrogenase, ev=1e-100, 48% identity; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 
 0.818
Dgeo_0850
TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase 2: (0); PFAM: aldehyde dehydrogenase: (2.6e-178); KEGG: dra:DR0813 1-pyrroline-5-carboxylate dehydrogenase, ev=0.0, 83% identity; Belongs to the aldehyde dehydrogenase family.
   
 
 0.810
Dgeo_1174
PFAM: aldehyde dehydrogenase: (3.9e-187); KEGG: dra:DRA0030 1-pyrroline-5-carboxylate dehydrogenase, ev=0.0, 76% identity; Belongs to the aldehyde dehydrogenase family.
   
 
 0.810
Dgeo_1203
PFAM: glutamine synthetase, catalytic region: (1.2e-16); KEGG: dra:DR2033 glutamine synthase, ev=0.0, 77% identity.
    
  0.806
purQ
Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...]
    
  0.805
Your Current Organism:
Deinococcus geothermalis
NCBI taxonomy Id: 319795
Other names: D. geothermalis DSM 11300, Deinococcus geothermalis AG-3a, Deinococcus geothermalis CIP 105573, Deinococcus geothermalis DSM 11300, Deinococcus geothermalis str. DSM 11300, Deinococcus geothermalis strain DSM 11300
Server load: medium (72%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.