node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dgeo_1532 | kynB | Dgeo_1532 | Dgeo_1533 | KEGG: dra:DR0909 hypothetical protein, ev=2e-42, 50% identity. | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | 0.673 |
Dgeo_1532 | kynU | Dgeo_1532 | Dgeo_1534 | KEGG: dra:DR0909 hypothetical protein, ev=2e-42, 50% identity. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.673 |
Dgeo_2154 | Dgeo_2155 | Dgeo_2154 | Dgeo_2155 | Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+); PFAM: malic enzyme-like: (3.1e-105) malic enzyme, NAD-binding: (1.4e-109); KEGG: dra:DRA0276 malate oxidoreductase, ev=0.0, 71% identity. | PFAM: malic enzyme-like: (9.3e-106) malic enzyme, NAD-binding: (1.1e-109); KEGG: dra:DR2583 malate oxidoreductase, ev=0.0, 73% identity. | 0.959 |
Dgeo_2154 | fumC | Dgeo_2154 | Dgeo_2328 | Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+); PFAM: malic enzyme-like: (3.1e-105) malic enzyme, NAD-binding: (1.4e-109); KEGG: dra:DRA0276 malate oxidoreductase, ev=0.0, 71% identity. | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.937 |
Dgeo_2154 | kynB | Dgeo_2154 | Dgeo_1533 | Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+); PFAM: malic enzyme-like: (3.1e-105) malic enzyme, NAD-binding: (1.4e-109); KEGG: dra:DRA0276 malate oxidoreductase, ev=0.0, 71% identity. | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | 0.800 |
Dgeo_2154 | mdh | Dgeo_2154 | Dgeo_2161 | Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+); PFAM: malic enzyme-like: (3.1e-105) malic enzyme, NAD-binding: (1.4e-109); KEGG: dra:DRA0276 malate oxidoreductase, ev=0.0, 71% identity. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.933 |
Dgeo_2155 | Dgeo_2154 | Dgeo_2155 | Dgeo_2154 | PFAM: malic enzyme-like: (9.3e-106) malic enzyme, NAD-binding: (1.1e-109); KEGG: dra:DR2583 malate oxidoreductase, ev=0.0, 73% identity. | Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+); PFAM: malic enzyme-like: (3.1e-105) malic enzyme, NAD-binding: (1.4e-109); KEGG: dra:DRA0276 malate oxidoreductase, ev=0.0, 71% identity. | 0.959 |
Dgeo_2155 | fumC | Dgeo_2155 | Dgeo_2328 | PFAM: malic enzyme-like: (9.3e-106) malic enzyme, NAD-binding: (1.1e-109); KEGG: dra:DR2583 malate oxidoreductase, ev=0.0, 73% identity. | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.937 |
Dgeo_2155 | kynB | Dgeo_2155 | Dgeo_1533 | PFAM: malic enzyme-like: (9.3e-106) malic enzyme, NAD-binding: (1.1e-109); KEGG: dra:DR2583 malate oxidoreductase, ev=0.0, 73% identity. | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | 0.800 |
Dgeo_2155 | mdh | Dgeo_2155 | Dgeo_2161 | PFAM: malic enzyme-like: (9.3e-106) malic enzyme, NAD-binding: (1.1e-109); KEGG: dra:DR2583 malate oxidoreductase, ev=0.0, 73% identity. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.933 |
fumC | Dgeo_2154 | Dgeo_2328 | Dgeo_2154 | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+); PFAM: malic enzyme-like: (3.1e-105) malic enzyme, NAD-binding: (1.4e-109); KEGG: dra:DRA0276 malate oxidoreductase, ev=0.0, 71% identity. | 0.937 |
fumC | Dgeo_2155 | Dgeo_2328 | Dgeo_2155 | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | PFAM: malic enzyme-like: (9.3e-106) malic enzyme, NAD-binding: (1.1e-109); KEGG: dra:DR2583 malate oxidoreductase, ev=0.0, 73% identity. | 0.937 |
fumC | kynB | Dgeo_2328 | Dgeo_1533 | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | 0.800 |
fumC | mdh | Dgeo_2328 | Dgeo_2161 | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.964 |
kynB | Dgeo_1532 | Dgeo_1533 | Dgeo_1532 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | KEGG: dra:DR0909 hypothetical protein, ev=2e-42, 50% identity. | 0.673 |
kynB | Dgeo_2154 | Dgeo_1533 | Dgeo_2154 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | Malate dehydrogenase (oxaloacetate decarboxylating) (NADP+); PFAM: malic enzyme-like: (3.1e-105) malic enzyme, NAD-binding: (1.4e-109); KEGG: dra:DRA0276 malate oxidoreductase, ev=0.0, 71% identity. | 0.800 |
kynB | Dgeo_2155 | Dgeo_1533 | Dgeo_2155 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | PFAM: malic enzyme-like: (9.3e-106) malic enzyme, NAD-binding: (1.1e-109); KEGG: dra:DR2583 malate oxidoreductase, ev=0.0, 73% identity. | 0.800 |
kynB | fumC | Dgeo_1533 | Dgeo_2328 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.800 |
kynB | kynU | Dgeo_1533 | Dgeo_1534 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.998 |
kynB | mdh | Dgeo_1533 | Dgeo_2161 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.800 |