STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (295 aa)    
Predicted Functional Partners:
murC
UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
 0.999
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
 
  
 0.976
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
  
 0.938
Dgeo_1633
Cell division protein FtsQ; Essential cell division protein.
 
  
 0.925
ddl
D-alanine--D-alanine ligase; Cell wall formation.
  
 0.922
ftsA
Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.
     
 0.854
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
     
 0.828
Dgeo_2140
TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase: (9.3e-34) Helix-turn-helix biotin operon repressor region: (3.4e-19); PFAM: biotin protein ligase-like: (5.6e-05) biotin/lipoate A/B protein ligase: (1.8e-16); KEGG: dra:DR2341 birA bifunctional protein, ev=1e-111, 69% identity.
  
  
 0.787
Dgeo_1723
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.
 
  
 0.687
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.674
Your Current Organism:
Deinococcus geothermalis
NCBI taxonomy Id: 319795
Other names: D. geothermalis DSM 11300, Deinococcus geothermalis AG-3a, Deinococcus geothermalis CIP 105573, Deinococcus geothermalis DSM 11300, Deinococcus geothermalis str. DSM 11300, Deinococcus geothermalis strain DSM 11300
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