node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dgeo_0003 | Dgeo_0461 | Dgeo_0003 | Dgeo_0461 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: dra:DR0354 exodeoxyribonuclease III, ev=1e-100, 70% identity; TIGRFAM: exodeoxyribonuclease III: (3.6e-54) exodeoxyribonuclease III (xth): (5.4e-65); PFAM: Endonuclease/exonuclease/phosphatase: (1.2e-47). | 0.939 |
Dgeo_0003 | polA | Dgeo_0003 | Dgeo_1666 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.999 |
Dgeo_0003 | recA | Dgeo_0003 | Dgeo_2138 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.834 |
Dgeo_0003 | ung | Dgeo_0003 | Dgeo_2059 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.667 |
Dgeo_0461 | Dgeo_0003 | Dgeo_0461 | Dgeo_0003 | KEGG: dra:DR0354 exodeoxyribonuclease III, ev=1e-100, 70% identity; TIGRFAM: exodeoxyribonuclease III: (3.6e-54) exodeoxyribonuclease III (xth): (5.4e-65); PFAM: Endonuclease/exonuclease/phosphatase: (1.2e-47). | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.939 |
Dgeo_0461 | nth | Dgeo_0461 | Dgeo_0248 | KEGG: dra:DR0354 exodeoxyribonuclease III, ev=1e-100, 70% identity; TIGRFAM: exodeoxyribonuclease III: (3.6e-54) exodeoxyribonuclease III (xth): (5.4e-65); PFAM: Endonuclease/exonuclease/phosphatase: (1.2e-47). | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.963 |
Dgeo_0461 | polA | Dgeo_0461 | Dgeo_1666 | KEGG: dra:DR0354 exodeoxyribonuclease III, ev=1e-100, 70% identity; TIGRFAM: exodeoxyribonuclease III: (3.6e-54) exodeoxyribonuclease III (xth): (5.4e-65); PFAM: Endonuclease/exonuclease/phosphatase: (1.2e-47). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.951 |
Dgeo_0461 | recA | Dgeo_0461 | Dgeo_2138 | KEGG: dra:DR0354 exodeoxyribonuclease III, ev=1e-100, 70% identity; TIGRFAM: exodeoxyribonuclease III: (3.6e-54) exodeoxyribonuclease III (xth): (5.4e-65); PFAM: Endonuclease/exonuclease/phosphatase: (1.2e-47). | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.422 |
Dgeo_0461 | ung | Dgeo_0461 | Dgeo_2059 | KEGG: dra:DR0354 exodeoxyribonuclease III, ev=1e-100, 70% identity; TIGRFAM: exodeoxyribonuclease III: (3.6e-54) exodeoxyribonuclease III (xth): (5.4e-65); PFAM: Endonuclease/exonuclease/phosphatase: (1.2e-47). | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.876 |
Dgeo_1579 | recA | Dgeo_1579 | Dgeo_2138 | TIGRFAM: DNA internalization-related competence protein ComEC/Rec2: (7e-56); PFAM: beta-lactamase-like: (1.2e-06) ComEC/Rec2-related protein: (5.8e-44); KEGG: dra:DR1854 competence protein ComEC/Rec2, putative, ev=0.0, 68% identity. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.601 |
Dgeo_1579 | ung | Dgeo_1579 | Dgeo_2059 | TIGRFAM: DNA internalization-related competence protein ComEC/Rec2: (7e-56); PFAM: beta-lactamase-like: (1.2e-06) ComEC/Rec2-related protein: (5.8e-44); KEGG: dra:DR1854 competence protein ComEC/Rec2, putative, ev=0.0, 68% identity. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.407 |
Dgeo_2058 | carA | Dgeo_2058 | Dgeo_2060 | DNA topoisomerase IB; KEGG: dra:DR0690 type I topoisomerase, putative, ev=1e-144, 74% identity. | TIGRFAM: carbamoyl-phosphate synthase, small subunit: (6.3e-239); PFAM: glutamine amidotransferase class-I: (1.9e-65) Carbamoyl-phosphate synthase, small chain: (1.3e-72); KEGG: dra:DR0684 carbamoyl-phosphate synthase small chain, ev=0.0, 95% identity; Belongs to the CarA family. | 0.614 |
Dgeo_2058 | polA | Dgeo_2058 | Dgeo_1666 | DNA topoisomerase IB; KEGG: dra:DR0690 type I topoisomerase, putative, ev=1e-144, 74% identity. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.531 |
Dgeo_2058 | ung | Dgeo_2058 | Dgeo_2059 | DNA topoisomerase IB; KEGG: dra:DR0690 type I topoisomerase, putative, ev=1e-144, 74% identity. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.858 |
carA | Dgeo_2058 | Dgeo_2060 | Dgeo_2058 | TIGRFAM: carbamoyl-phosphate synthase, small subunit: (6.3e-239); PFAM: glutamine amidotransferase class-I: (1.9e-65) Carbamoyl-phosphate synthase, small chain: (1.3e-72); KEGG: dra:DR0684 carbamoyl-phosphate synthase small chain, ev=0.0, 95% identity; Belongs to the CarA family. | DNA topoisomerase IB; KEGG: dra:DR0690 type I topoisomerase, putative, ev=1e-144, 74% identity. | 0.614 |
carA | ung | Dgeo_2060 | Dgeo_2059 | TIGRFAM: carbamoyl-phosphate synthase, small subunit: (6.3e-239); PFAM: glutamine amidotransferase class-I: (1.9e-65) Carbamoyl-phosphate synthase, small chain: (1.3e-72); KEGG: dra:DR0684 carbamoyl-phosphate synthase small chain, ev=0.0, 95% identity; Belongs to the CarA family. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.573 |
nth | Dgeo_0461 | Dgeo_0248 | Dgeo_0461 | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | KEGG: dra:DR0354 exodeoxyribonuclease III, ev=1e-100, 70% identity; TIGRFAM: exodeoxyribonuclease III: (3.6e-54) exodeoxyribonuclease III (xth): (5.4e-65); PFAM: Endonuclease/exonuclease/phosphatase: (1.2e-47). | 0.963 |
nth | polA | Dgeo_0248 | Dgeo_1666 | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.743 |
nth | ung | Dgeo_0248 | Dgeo_2059 | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. | 0.597 |
polA | Dgeo_0003 | Dgeo_1666 | Dgeo_0003 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.999 |