| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acpP | bioF | AMF_253 | AMF_199 | Acyl carrier protein (acpP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 8-amino-7-oxononanoate synthase; Psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0156 BioF 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.642 |
| acpP | dhkA | AMF_253 | AMF_369 | Acyl carrier protein (acpP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | Sensory box histidine kinase/response regulator (dhkA); Psort: bacterial inner membrane --- Certainty= 0.491(Affirmative); COG0642 Signal transduction histidine kinase. | 0.581 |
| acpP | fabD | AMF_253 | AMF_077 | Acyl carrier protein (acpP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | Malonyl CoA-acyl carrier protein transacylase (fabD); Psort: bacterial cytoplasm --- Certainty= 0.118(Affirmative); COG0331 FabD (acyl-carrier-protein) S-malonyltransferase. | 0.990 |
| bioA | bioB | AMF_413 | AMF_742 | Psort: bacterial cytoplasm --- Certainty= 0.133(Affirmative); COG0161 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.979 |
| bioA | bioF | AMF_413 | AMF_199 | Psort: bacterial cytoplasm --- Certainty= 0.133(Affirmative); COG0161 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; Psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0156 BioF 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.979 |
| bioA | dtbS | AMF_413 | AMF_853 | Psort: bacterial cytoplasm --- Certainty= 0.133(Affirmative); COG0161 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthase (dtbS); Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.998 |
| bioA | ribD | AMF_413 | AMF_013 | Psort: bacterial cytoplasm --- Certainty= 0.133(Affirmative); COG0161 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Riboflavin biosynthesis protein (ribD); Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.482 |
| bioB | bioA | AMF_742 | AMF_413 | Biotin synthase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Psort: bacterial cytoplasm --- Certainty= 0.133(Affirmative); COG0161 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.979 |
| bioB | bioF | AMF_742 | AMF_199 | Biotin synthase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 8-amino-7-oxononanoate synthase; Psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0156 BioF 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.756 |
| bioB | dtbS | AMF_742 | AMF_853 | Biotin synthase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Dethiobiotin synthase (dtbS); Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.997 |
| bioB | fabD | AMF_742 | AMF_077 | Biotin synthase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Malonyl CoA-acyl carrier protein transacylase (fabD); Psort: bacterial cytoplasm --- Certainty= 0.118(Affirmative); COG0331 FabD (acyl-carrier-protein) S-malonyltransferase. | 0.526 |
| bioB | metK | AMF_742 | AMF_973 | Biotin synthase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | S-adenosylmethionine synthetase (metK); Psort: bacterial inner membrane --- Certainty= 0.121(Affirmative); COG0192 MetK S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | 0.426 |
| bioB | ribD | AMF_742 | AMF_013 | Biotin synthase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Riboflavin biosynthesis protein (ribD); Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.476 |
| bioF | acpP | AMF_199 | AMF_253 | 8-amino-7-oxononanoate synthase; Psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0156 BioF 7-keto-8-aminopelargonate synthetase and related enzymes. | Acyl carrier protein (acpP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.642 |
| bioF | bioA | AMF_199 | AMF_413 | 8-amino-7-oxononanoate synthase; Psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0156 BioF 7-keto-8-aminopelargonate synthetase and related enzymes. | Psort: bacterial cytoplasm --- Certainty= 0.133(Affirmative); COG0161 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.979 |
| bioF | bioB | AMF_199 | AMF_742 | 8-amino-7-oxononanoate synthase; Psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0156 BioF 7-keto-8-aminopelargonate synthetase and related enzymes. | Biotin synthase (bioB); Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.756 |
| bioF | dhkA | AMF_199 | AMF_369 | 8-amino-7-oxononanoate synthase; Psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0156 BioF 7-keto-8-aminopelargonate synthetase and related enzymes. | Sensory box histidine kinase/response regulator (dhkA); Psort: bacterial inner membrane --- Certainty= 0.491(Affirmative); COG0642 Signal transduction histidine kinase. | 0.569 |
| bioF | dtbS | AMF_199 | AMF_853 | 8-amino-7-oxononanoate synthase; Psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0156 BioF 7-keto-8-aminopelargonate synthetase and related enzymes. | Dethiobiotin synthase (dtbS); Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.949 |
| bioF | fabD | AMF_199 | AMF_077 | 8-amino-7-oxononanoate synthase; Psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0156 BioF 7-keto-8-aminopelargonate synthetase and related enzymes. | Malonyl CoA-acyl carrier protein transacylase (fabD); Psort: bacterial cytoplasm --- Certainty= 0.118(Affirmative); COG0331 FabD (acyl-carrier-protein) S-malonyltransferase. | 0.572 |
| bioF | guaA | AMF_199 | AMF_897 | 8-amino-7-oxononanoate synthase; Psort: bacterial inner membrane --- Certainty= 0.132(Affirmative); COG0156 BioF 7-keto-8-aminopelargonate synthetase and related enzymes. | GMP synthase (glutamine-hydrolyzing) (guaA); Catalyzes the synthesis of GMP from XMP. | 0.466 |