STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pycApropionyl-CoA carboxylase alpha chain precursor (pycA); Psort: bacterial membrane --- Certainty= 0.771(Affirmative); COG1038 PycA pyruvate carboxylase, C-terminal domain/subunit. (662 aa)    
Predicted Functional Partners:
pccB
propionyl-COA carboxylase beta chain precursor (pccB); Psort: bacterial inner membrane --- Certainty= 0.042(Affirmative); COG0825 AccA Acetyl-CoA carboxylase alpha subunit.
 
 0.999
birA
biotin-(acetyl-CoA carboxylase) (birA); Psort: bacterial inner membrane --- Certainty= 0.145(Affirmative); COG0340 BirA biotin-(acetyl-CoA carboxylase) ligase.
 
  
 0.965
rpoZ
DNA-directed RNA polymerase omega subunit (rpoZ); Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
  0.937
rpoA
DNA-directed RNA polymerase alpha chain (rpoA); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.918
rpoB
RNA polymerase beta subunit (rpoB); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.917
fabB
3-oxoacyl-(acyl-carrier-protein) synthase II (fabB); Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
  
 0.798
fabZ
(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase (fabZ); Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
  
  
 0.756
fabD
Malonyl CoA-acyl carrier protein transacylase (fabD); Psort: bacterial cytoplasm --- Certainty= 0.118(Affirmative); COG0331 FabD (acyl-carrier-protein) S-malonyltransferase.
 
  
 0.723
pdhB
Pyruvate dehydrogenase E1 beta subunit precursor (pdhB); The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.600
maeB
Malate dehydrogenase and phosphate acetyltransferase (maeB); Psort: bacterial inner membrane --- Certainty= 0.140(Affirmative); COG0039 Mdh malate/lactate dehydrogenases.
  
  
 0.585
Your Current Organism:
Anaplasma marginale
NCBI taxonomy Id: 320483
Other names: A. marginale str. Florida, Anaplasma marginale str. Florida, Anaplasma marginale strain Florida
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.