STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kaiACircadian clock protein KaiA; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of KaiC. In contrast, the presence of KaiB in the complex decreases the phosphorylation status of KaiC, suggesting that KaiB acts by antagonizing the interaction between KaiA and KaiC. A KaiA dimer is sufficient to enhance KaiC he [...] (299 aa)    
Predicted Functional Partners:
kaiC
Circadian clock protein KaiC; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family.
   
 
 0.999
kaiB
Circadian clock protein KaiB; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC; Belongs to the KaiB family.
   
 
 0.999
kaiB-2
Circadian clock protein KaiB; Similar to slr0757 of Synechocystis sp. PCC 6803.
   
 
 0.987
ACB00667.1
Conserved hypothetical protein; Similar to sll1247 of Synechocystis sp. PCC 6803.
  
     0.761
ACA98783.1
Conserved hypothetical protein; Similar to sll0319 of Synechocystis sp. PCC 6803.
  
     0.747
ACA99484.1
Conserved hypothetical protein; Similar to sll1942 in Synechocystis sp. PCC 6803.
  
     0.731
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
      
 0.730
ACB00093.1
Conserved hypothetical protein; Similar to sll0858 of Synechocystis sp. PCC 6803.
  
     0.711
ndhL
NADH dehydrogenase subunit L (inorganic carbon tranpsort protein); NDH-1 shuttles electrons from an unknown electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and/or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon-concentration.
  
     0.701
ACA98305.1
Two-component hybrid sensor and regulator; Similar to alr3159 of Nostoc sp. PCC 7120.
   
 
 0.690
Your Current Organism:
Synechococcus sp. PCC7002
NCBI taxonomy Id: 32049
Other names: Agmenellum quadruplicatum, Agmenellum quadruplicatum PR-6, S. sp. PCC 7002, Synechococcus PCC7002 PR-6, Synechococcus sp. (ATCC 27264), Synechococcus sp. (PCC 7002), Synechococcus sp. (strain PCC 7002), Synechococcus sp. PCC 7002
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