node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACA99172.1 | ACA99966.1 | SYNPCC7002_A1173 | SYNPCC7002_A1979 | Polyketide synthase. | AMP-binding enzyme; Similar to alr2678 of Nostoc sp. PCC 7120. | 0.999 |
ACA99172.1 | bioB | SYNPCC7002_A1173 | SYNPCC7002_A0309 | Polyketide synthase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.541 |
ACA99172.1 | bioD | SYNPCC7002_A1173 | SYNPCC7002_A2727 | Polyketide synthase. | Putative dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.635 |
ACA99172.1 | bioF | SYNPCC7002_A1173 | SYNPCC7002_A1281 | Polyketide synthase. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.730 |
ACA99172.1 | bioY | SYNPCC7002_A1173 | SYNPCC7002_A0310 | Polyketide synthase. | BioY protein; Similar to slr1365 of Synechocystis sp. PCC 6803; precise function unknown but thought to play a role in biotin biosynthesis. | 0.462 |
ACA99172.1 | birA | SYNPCC7002_A1173 | SYNPCC7002_A0084 | Polyketide synthase. | biotin-acetyl-CoA-carboxylase ligase. | 0.642 |
ACA99966.1 | ACA99172.1 | SYNPCC7002_A1979 | SYNPCC7002_A1173 | AMP-binding enzyme; Similar to alr2678 of Nostoc sp. PCC 7120. | Polyketide synthase. | 0.999 |
ACA99966.1 | bioB | SYNPCC7002_A1979 | SYNPCC7002_A0309 | AMP-binding enzyme; Similar to alr2678 of Nostoc sp. PCC 7120. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.871 |
ACA99966.1 | bioD | SYNPCC7002_A1979 | SYNPCC7002_A2727 | AMP-binding enzyme; Similar to alr2678 of Nostoc sp. PCC 7120. | Putative dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.938 |
ACA99966.1 | bioF | SYNPCC7002_A1979 | SYNPCC7002_A1281 | AMP-binding enzyme; Similar to alr2678 of Nostoc sp. PCC 7120. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.570 |
ACA99966.1 | bioY | SYNPCC7002_A1979 | SYNPCC7002_A0310 | AMP-binding enzyme; Similar to alr2678 of Nostoc sp. PCC 7120. | BioY protein; Similar to slr1365 of Synechocystis sp. PCC 6803; precise function unknown but thought to play a role in biotin biosynthesis. | 0.510 |
ACA99966.1 | birA | SYNPCC7002_A1979 | SYNPCC7002_A0084 | AMP-binding enzyme; Similar to alr2678 of Nostoc sp. PCC 7120. | biotin-acetyl-CoA-carboxylase ligase. | 0.527 |
bioB | ACA99172.1 | SYNPCC7002_A0309 | SYNPCC7002_A1173 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Polyketide synthase. | 0.541 |
bioB | ACA99966.1 | SYNPCC7002_A0309 | SYNPCC7002_A1979 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | AMP-binding enzyme; Similar to alr2678 of Nostoc sp. PCC 7120. | 0.871 |
bioB | bioD | SYNPCC7002_A0309 | SYNPCC7002_A2727 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Putative dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.997 |
bioB | bioF | SYNPCC7002_A0309 | SYNPCC7002_A1281 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.864 |
bioB | bioY | SYNPCC7002_A0309 | SYNPCC7002_A0310 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | BioY protein; Similar to slr1365 of Synechocystis sp. PCC 6803; precise function unknown but thought to play a role in biotin biosynthesis. | 0.896 |
bioB | birA | SYNPCC7002_A0309 | SYNPCC7002_A0084 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | biotin-acetyl-CoA-carboxylase ligase. | 0.939 |
bioB | folB | SYNPCC7002_A0309 | SYNPCC7002_A0307 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.590 |
bioB | folK | SYNPCC7002_A0309 | SYNPCC7002_A0306 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.560 |